Fig. 4
From: Unraveling the complexity of STAT3 in cancer: molecular understanding and drug discovery
Summary of STAT3 direct inhibitors and indirect inhibitors and the combination strategies. Upper panel, an overview of STAT3 direct inhibitors and indirect inhibitors. Lower panel, STAT3 inhibitors in combination with chemotherapy, radiotherapy, targeted therapy, immunotherapy, and dual-inhibiting of STAT3 mediate metabolic alteration of tumor cells and immune cells. Created with BioRender.com