Fig. 6
From: EGR1 suppresses HCC growth and aerobic glycolysis by transcriptionally downregulating PFKL
EGR1 inhibited HCC cells proliferation by downregulating PFKL-mediated aerobic glycolysis. A The WB analysis was conducted on PFKL and EGR1 in EGR1 overexpressing PLC/PRF5 cells after PFKL restoration. B, C, D, E, F, G PFKL restoration was observed to reverse the inhibitory effects of EGR1 on glucose uptake, extracellular lactate levels, glycolysis and glycolytic capacity, ATP levels, cell proliferation and colony formation capacity. **P < 0.01, ***P < 0.001, ****P < 0.0001