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Table 1 Associations of ZCCHC4 expression with clinical parameters in CRC

From: The epigenetic downregulation of LncGHRLOS mediated by RNA m6A methylase ZCCHC4 promotes colorectal cancer tumorigenesis

Varibles

 

ZCCHC4 expression

P value

Low(n = 68)

High(n = 175)

Gender

Female

33

69

0.104

 

Male

35

106

 

Age

>55

49

112

0.076

 

≤ 55

19

63

 

Tumor size

>3.5 cm

44

90

0.081

 

≤ 3.5 cm

24

85

 

Vascular invasion

Positive

15

42

0.102

 

Negative

53

133

 

Nerve invasion

Positive

13

37

0.113

 

Negative

55

138

 

Differentiation degree

High/median

40

71

0.027

 

Low

28

104

 

Depth of infiltration

T1/T2

29

80

0.097

 

T3/T4

39

95

 

Positive lymph nodes

≥ 3

20

84

0.0877

 

<3

40

99

 

TNM stage

I/II

41

66

0.008

 

III/IV

27

109

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