Fig. 9From: A tumor suppressor protein encoded by circKEAP1 inhibits osteosarcoma cell stemness and metastasis by promoting vimentin proteasome degradation and activating anti-tumor immunitySchematic diagram of the project. In OS, circKEAP1 inhibits cell proliferation, migration and stemness by encoding a novel protein KEAP1-259aa, which mediated ubiquitination and stability of vimentin as well as triggers an immune defense response via the RIG-I pathwayBack to article page