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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: MUC20 regulated by extrachromosomal circular DNA attenuates proteasome inhibitor resistance of multiple myeloma by modulating cuproptosis

Fig. 2

MUC20 levels are predictive of proteasome inhibitor sensitivity and outcome of MM patients. A Analysis of the ORR and PD in patients with MM with high and low MUC20 expression after BTZ treatment. B Kaplan–Meier survival analysis of PFS and OS in patients with MM with high and low MUC20 expression. C Analysis of ORR and PD in patients with MM with high and low MUC20 expression after dexamethasone treatment. D Kaplan–Meier survival analysis of PFS and OS in patients with MM high and low MUC20 expression after dexamethasone treatment. E Analysis of the ORR and PD in patients with NDMM with high and low MUC20 expression after BTZ treatment. F Kaplan–Meier survival analysis of the PFS and OS in patients with NDMM with high and low MUC20 expression after BTZ treatment. BTZ: bortezomib; ORR: overall response rate; PD: progressive disease; PFS: progression free survival; OS: overall survival

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