Fig. 4

Targeting FAK in combination with doxorubicin significantly boosts the maturation of dendritic cells (DCs) in vitro. A-D The staining of DCs maturation biomarkers in mixed cells of treated 4T1 /CT26 and bone marrow cell pools. The 4T1 and bone marrow cells were processed as indicated in the Methods. The data were processed using GraphPad Prism 8.0 software. E–H The staining of DCs maturation biomarkers in mixed cells of treated CT26 and bone marrow cell pools. The data were analyzed by flow cytometry and processed with GraphPad Prism 8.0 software (n ≥ 3 per group). Data represent mean ± SEM. Statistics analysis was done using the unpaired student's T-test. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001