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Table 1 High ELR+CXCL expression is associated with poor OS under ICI in RCC patients. ELR+CXCLs levels (CXCL1, CXCL2, CXCL3, CXCL5, CXCL8) and PD-L1 mRNA expression in patients with metastatic RCC treated with ICIs or everolimus were measured by NGS and correlated with OS in patients from our cohort (ICI treatment, 56 patients, a and from the published cohort (ICI treatment, 181 patients, b or everolimus treatment, 130 patients, c. The third quartile value of CXCLs expression was chosen as the cut-off value and correlated with OS. The Kaplan–Meier method was used to generate survival curves and analyses of censored data were performed using Cox models. Statistical significance (p-values) is indicated

From: Unveiling CXCR2 as a promising therapeutic target in renal cell carcinoma: exploring the immunotherapeutic paradigm shift through its inhibition by RCT001