N6-methyladenosine-modified circSLCO1B3 promotes intrahepatic cholangiocarcinoma progression via regulating HOXC8 and PD-L1

Table 1 Clinical information and circSLCO1B3 expression in ICC patients

Parameters	Number of cases	CircSLCO1B3 expression (Average Intensity)		χ²	P value
		Low	High
All cases	93	42	51
Age				*3.587*	*0.058*
<48	60	14	46
≥48	36	15	21
Gender				0.228	0.633
Male	60	26	34
Female	33	16	17
Histological differentiation				*4.207*	*0.04*
Moderately differentiated	38	22	16
Poorly differentiated	55	20	35
TNM				0.290	0.590
TI-TII	57	27	30
TIII-TIV	36	15	21
Tumour size				*7.990*	*0.005*
≤5cm	43	23	10
>5cm	50	19	31
Lymph node metastatic				*7.168*	*0.007*
Yes	18	5	13
No	75	47	28
CA19-9				0.861	0.353
≤35u/ml	40	18	22
>35u/ml	53	29	24

ISSN: 1756-9966