Fig. 5
From: Anaplastic thyroid cancer spheroids as preclinical models to test therapeutics
Histological characterization and marker expression analysis of anaplastic thyroid cancer (ATC) spheroids. (A) Hematoxylin-eosin (HE) staining of ATC01 primary tumor tissues and tumor-derived spheroids. Immunohistochemistry staining of Ki-67, cytokeratin 19 (CK19), and thyroid transcription factor 1 (TTF-1) on ATC01 primary tumor tissues and tumor-derived spheroids. T = tumor, S = spheroid. Scale bars, 100 μm. (B) HE staining of ATC cell line-derived tumor spheroids. Immunohistochemistry staining of Ki-67, cytokeratin 19 (CK19), and thyroid transcription factor 1 (TTF-1) on ATC cell line-derived tumor spheroids. Scale bars, 400 μm