Table 1 Serum biochemistry profiles of Syrian hamsters after ADV-ApoA1 injection
|  |  | Control | 5 × 1012 VP/Kg (DRF-I.H.) | 1.2 × 1012 VP/Kg (DRF-I.V.) |
|---|---|---|---|---|
Male (n = 5) | ALT (U/L) | 72.2 ± 18.0 | 43.8 ± 9.7 | 49.6 ± 8.0 |
|  | AST (U/L) | 37.2 ± 4.8 | 34.6 ± 4.3 | 51.6 ± 13.2 |
|  | ALP (U/L) | 189.8 ± 8.2 | 232.0 ± 18.4 | 199.2 ± 20.1 |
|  | CK (U/L) | 818.4 ± 301.5 | 545.6 ± 239.7 | 789.4 ± 392.3 |
|  | LDH (U/L) | 145.6 ± 21.0 | 142.0 ± 26.9 | 193.0 ± 46.7 |
|  | AMY (U/L) | 1771.7 ± 242.7 | 2277.3 ± 260.4 | 1840.4 ± 144.1 |
|  | LIP (U/L) | 54.9 ± 5.1 | 37.0 ± 8.2 | 50.7 ± 7.6 |
|  | BUN (mmol/L) | 6.4 ± 1.1 | 5.7 ± 0.9 | 5.3 ± 0.5 |
|  | CREA (mmol/L) | 16.2 ± 3.4 | 14.0 ± 1.0 | 15.2 ± 0.8 |
|  | GLU (mmol/L) | 12.5 ± 1.7 | 9.3 ± 1.0 | 10.2 ± 2.3 |
Female (n = 5) | ALT (U/L) | 52.8 ± 7.1 | 35.4 ± 4.8 | 65.6 ± 23.7 |
|  | AST (U/L) | 40.8 ± 4.5 | 43.4 ± 4.8 | 59.4 ± 11.3 |
|  | ALP (U/L) | 201.2 ± 18.9 | 245.2 ± 22.4 | 201.4 ± 14.9 |
|  | CK (U/L) | 1005.4 ± 503.0 | 871.2 ± 458.9 | 1153.4 ± 395.6 |
|  | LDH (U/L) | 131.8 ± 31.1 | 149.6 ± 30.3 | 200.2 ± 47.5 |
|  | AMY (U/L) | 2487.7 ± 405.5 | 2551.1 ± 199.9 | 2375.0 ± 517.0 |
|  | LIP (U/L) | 54.5 ± 9.4 | 45.0 ± 7.0 | 45.7 ± 6.2 |
|  | BUN (mmol/L) | 7.0 ± 0.8 | 5.2 ± 0.8 | 6.4 ± 0.5 |
|  | CREA (mmol/L) | 18.8 ± 2.6 | 14.2 ± 3.6 | 16.2 ± 2.8 |
|  | GLU (mmol/L) | 10.3 ± 1.7 | 8.9 ± 2.0 | 8.8 ± 2.5 |