Fig. 3
From: A phenotypic screening approach to target p60AmotL2-expressing invasive cancer cells
A comprehensive proteomic analysis of proteins affected by p60AmotL2 expression. A Volcano plot showing the individual changes in 9,136 proteins in epithelial cells after induction of p60AmotL2. Different colors indicate filtering criteria; red represents proteins with a Log2 fold change > 0.5 or < -0.5 and Log10 P value < 0.05. Proteomics data can be found in Supplemental data 2. B Identified proteins were annotated by Gene Ontology (GO). C KEGG analysis of the identified proteins. D Immunohistochemical (IHC) staining of LAMC2 in lung cancer (upper panel) and colon cancer (lower panel). Images on the right represent insets shown as black squares in the images on the left. Left scale bar = 100 μm, right scale bar = 25 μm