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  1. Colorectal cancer (CRC) is one of the most common malignancies and is characterized by reprogrammed metabolism. Ferroptosis, a programmed cell death dependent on iron, has emerged as a promising strategy for C...

    Authors: Chang Xu, Zhixuan Bian, Xinyue Wang, Na Niu, Li Liu, Yixuan Xiao, Jiabei Zhu, Nan Huang, Yue Zhang, Yan Chen, Qi Wu, Fenyong Sun, Xiaoli Zhu and Qiuhui Pan
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:331
    Content type: Research Published on:

  2. CircRNA is recognized for its significant regulatory function across various cancers. However, its regulatory role in non-small cell lung cancer (NSCLC) is still largely uncharted.

    Authors: Yuanshan Yao, Chunji Chen, Jing Wang, Haojie Xuan, Xiuxiu Chen, Zheng Li, Fuzhi Yang, Bin Wang, Siyun Lin, Saitian Li, Dongfang Tang, Libao Gong and Wen Gao
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:330
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2023 42:345

  3. Hedgehog-Gli1 signaling induces development of two common neurological features seen in pancreatic ductal adenocarcinoma (PDAC): peripheral neural invasion (PNI) and peripheral neural remodeling (PNR). However...

    Authors: Weiqi Dai, Xiaoli Wu, Jingjing Li, Wenxi Tang, Ying Wang, Wenqiang Xu, Dengyu Han, Xiaorong Xu and Xuanfu Xu
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:329
    Content type: Research Published on:

  4. Lung metastasis is the most adverse clinical factor and remains the leading cause of osteosarcoma-related death. Deciphering the mechanisms driving metastatic spread is crucial for finding open therapeutic win...

    Authors: Sara F.F. Almeida, Liliana Santos, Gabriela Sampaio-Ribeiro, Hugo R.S. Ferreira, Nuno Lima, Rui Caetano, Mónica Abreu, Mónica Zuzarte, Ana Sofia Ribeiro, Artur Paiva, Tânia Martins-Marques, Paulo Teixeira, Rui Almeida, José Manuel Casanova, Henrique Girão, Antero J. Abrunhosa…
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:328
    Content type: Research Published on:

  6. As a small G protein of Ras family, Ras-like-without-CAAX-1 (RIT1) plays a critical role in various tumors. Our previous study has demonstrated the involvement of RIT1 in promoting malignant progression of hep...

    Authors: Yang Su, Hechun Lin, Junming Yu, Lin Mao, Wenjiao Jin, Tengfei Liu, Shuqing Jiang, Yunyu Wu, Saihua Zhang, Qin Geng, Chao Ge, Fangyu Zhao, Taoyang Chen, Ying Cui, Jinjun Li, Helei Hou…
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:326
    Content type: Research Published on:

  7. Breast cancer is the global leading cancer burden in women and the hormone receptor-positive (HR+) subtype is a major part of breast cancer. Though cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors are highl...

    Authors: Nar Bahadur Katuwal, Min Sil Kang, Mithun Ghosh, Sa Deok Hong, Yeong Gyu Jeong, Seong Min Park, Seul-Gi Kim, Joohyuk Sohn, Tae Hoen Kim and Yong Wha Moon
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:325
    Content type: Research Published on:

  8. Cancer-associated fibroblasts (CAFs) play pivotal roles in chemoresistance of pancreatic ductal adenocarcinoma (PDAC). However, the underlying mechanisms are poorly understood. Revealing the cross-talk network...

    Authors: Shangyou Zheng, Qing Tian, Yuan Yuan, Shuxin Sun, Tingting Li, Renpeng Xia, Rihua He, Yuming Luo, Qing Lin, Zhiqiang Fu, Yu Zhou, Rufu Chen and Chonghui Hu
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:324
    Content type: Research Published on:

  9. Pancreatic ductal adenocarcinoma (PDAC) is a profoundly aggressive and fatal cancer. One of the key factors defining its aggressiveness and resilience against chemotherapy is the existence of cancer stem cells...

    Authors: Quan Zheng, Jiajia Tang, Alexandra Aicher, Tony Bou Kheir, Berina Sabanovic, Preeta Ananthanarayanan, Chiara Reina, Minchun Chen, Jian-Min Gu, Bin He, Sonia Alcala, Diana Behrens, Rita T. Lawlo, Aldo Scarpa, Manuel Hidalgo, Bruno Sainz Jr.…
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:323
    Content type: Research Published on:

  10. Lines of evidence indicated that, immune checkpoints (ICs) inhibitors enhanced T cell immune response to exert anti-tumor effects. However, T cell exhaustion has been so far a major obstacle to antitumor immun...

    Authors: Yan Lv, Mengyuan Li, Ling Weng, Haoying Huang, Yujie Mao, Danchen Aaron Yang, Qingyun Wei, Mengmeng Zhao, Qin Wei, Ke Rui, Xuan Han, Weiwei Fan, Xueting Cai, Peng Cao and Meng Cao
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:322
    Content type: Research Published on:

  11. Authors: Jianfa Li, Chengle Zhuang, Yuchen Liu, Mingwei Chen, Yincong Chen, Zhicong Chen, Anbang He, Junhao Lin, Yonghao Zhan, Li Liu, Wen Xu, Guoping Zhao, Yinglu Guo, Hanwei Wu, Zhiming Cai and Weiren Huang
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:321
    Content type: Correction Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2016 35:99

  12. Epigenetic alterations play an important role in hepatocellular carcinoma (HCC) development. Enhancer of zeste homolog 2 (EZH2) is a well-known epigenetic modifier that functions as an oncogene in tumors by pr...

    Authors: Ke Wang, Xunliang Jiang, Yu Jiang, Jun Liu, Yongtao Du, Zecheng Zhang, Yunlong Li, Xinhui Zhao, Jipeng Li and Rui Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:320
    Content type: Research Published on:

  13. It has been demonstrated that circularRNA (circRNAs) plays a critical role in various cancers. While the potential molecular mechanism of circRNAs in the progression of colorectal cancer (CRC) remains uncertain.

    Authors: Jialin Song, Qing Liu, Lei Han, Tiantian Song, Sihao Huang, Xinyao Zhang, Qiuming He, Chenxi Liang, Shuai Zhu and Bin Xiong
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:319
    Content type: Research Published on:

  14. TGFβ induces several cell phenotypes including senescence, a stable cell cycle arrest accompanied by a secretory program, and epithelial-mesenchymal transition (EMT) in normal epithelial cells. During carcinog...

    Authors: Anda Huna, Jean-Michel Flaman, Catalina Lodillinsky, Kexin Zhu, Gabriela Makulyte, Victoria Pakulska, Yohann Coute, Clémence Ruisseaux, Pierre Saintigny, Hector Hernandez-Vargas, Pierre-Antoine Defossez, Mathieu Boissan, Nadine Martin and David Bernard
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:318
    Content type: Research Published on:

  15. BRAF-mutant melanoma patients benefit from the combinatorial treatments with BRAF and MEK inhibitors. However, acquired drug resistance strongly limits the efficacy of these targeted therapies in time. Recentl...

    Authors: Vittorio Castaldo, Michele Minopoli, Francesca Di Modugno, Andrea Sacconi, Domenico Liguoro, Rachele Frigerio, Arianna Ortolano, Marta Di Martile, Luisa Gesualdi, Gabriele Madonna, Mariaelena Capone, Roberto Cirombella, Angiolina Catizone, Donatella Del Bufalo, Andrea Vecchione, Maria Vincenza Carriero…
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:317
    Content type: Research Published on:

  16. Cancer-associated fibroblasts (CAFs), the predominant stromal cell of tumor microenvironment (TME), play an important role in tumor progression and immunoregulation by remodeling extracellular matrix (ECM) and...

    Authors: Zhao Zhang, Yongbo Yu, Zhilei Zhang, Dan Li, Zhijuan Liang, Liping Wang, Yuanbin Chen, Ye Liang and Haitao Niu
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:316
    Content type: Research Published on:

  17. Image-based screening improves the detection of early-stage lung adenocarcinoma (LUAD)but also highlights the issue of high false-positive diagnoses, which puts patients at a risk of unnecessary over-treatment...

    Authors: Yibei Wang, Ziwei Miao, Xiaoxue Qin, Yi Yang, Si Wu, Qi Miao, Beibei Li, Mingyu Zhang, Pengfei Wu, Yun Han and Bo Li
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:315
    Content type: Research Published on:

  18. Authors: Shanqiang Qu, Songtao Qi, Huayang Zhang, Zhiyong Li, Kaicheng Wang, Taichen Zhu, Rongxu Ye, Wanghao Zhang, Guanglong Huang and Guo-zhong Yi
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:314
    Content type: Correction Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2023 42:285

  19. Recent evidence reveals the emerging functions of circular RNA (circRNA) and protein glycosylation in cancer progression. However, the roles of circRNA in regulating glycosyltransferase expression in gastric c...

    Authors: Hongjun Li, Wanju Jiao, Jiyu Song, Jianqun Wang, Guo Chen, Dan Li, Xiaojing Wang, Banghe Bao, Xinyi Du, Yang Cheng, Chunhui Yang, Qiangsong Tong and Liduan Zheng
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:313
    Content type: Research Published on:

  20. Authors: Guosong Wang, Jiali Cao, Mengxuan Gui, Pengfei Huang, Liang Zhang, Ruoyao Qi, Ruiqi Chen, Lina Lin, Qiangyuan Han, Yanhua Lin, Tian Chen, Peiqing He, Jian Ma, Rao Fu, Junping Hong, Qian Wu…
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:312
    Content type: Correction Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2023 42:284

  21. Liver cancer stem cells (LCSCs) play an important role in hepatocellular carcinoma (HCC), but the mechanisms that link LCSCs to HCC metastasis remain largely unknown. This study aims to reveal the contribution...

    Authors: Lingyun Zhou, Linye He, Chang-Hai Liu, Huandi Qiu, Li Zheng, Klarke Michael Sample, Qin Wu, Jiaxin Li, Kunlin Xie, Javier Ampuero, Zhihui Li, Duoduo Lv, Miao Liu, Manuel Romero-Gómez, Yiguo Hu and Hong Tang
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:311
    Content type: Research Published on:

  22. Even acknowledging the game-changing results achieved in the treatment of metastatic melanoma with the use of immune checkpoint inhibitors (ICI), a large proportion of patients (40–60%) still fail to respond o...

    Authors: Lidia Giraudo, Giulia Cattaneo, Loretta Gammaitoni, Ilenia Iaia, Chiara Donini, Annamaria Massa, Maria Laura Centomo, Marco Basiricò, Elisa Vigna, Alberto Pisacane, Franco Picciotto, Enrico Berrino, Caterina Marchiò, Alessandra Merlini, Luca Paruzzo, Stefano Poletto…
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:310
    Content type: Research Published on:

  23. Recently, cancer organoid-based drug sensitivity tests have been studied to predict patient responses to anticancer drugs. The area under curve (AUC) or IC50 value of the dose-response curve (DRC) is used to diff...

    Authors: Sang-Yun Lee, Hyeong Jun Cho, Jimin Choi, Bosung Ku, Seok Whan Moon, Mi Hyoung Moon, Kyung Soo Kim, Kwanyong Hyun, Tae-Jung Kim, Yeoun Eun Sung, Yongki Hwang, Eunyoung Lee, Dong Hyuck Ahn, Joon Young Choi, Jeong Uk Lim, Chan Kwon Park…
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:309
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2023 42:332

  24. Colorectal cancer (CRC) is one of the most common malignant cancers worldwide and seriously threatens human health. The clustered regulatory interspaced short palindromic repeat/CRISPR-associate nuclease 9 (CR...

    Authors: Yang Hu, Liang Liu, Qi Jiang, Weiping Fang, Yazhu Chen, Yuntian Hong and Xiang Zhai
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:308
    Content type: Review Published on:

  25. Authors: Jian-Xian Lin, Xin-Sheng Xie, Xiong-Feng Weng, Sheng-Liang Qiu, Changhwan Yoon, Ning-Zi Lian, Jian-Wei Xie, Jia-Bin Wang, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Ru-Hong Tu, Ying-Hong Yang, Chang-Ming Huang, Chao-Hui Zheng…
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:307
    Content type: Correction Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2019 38:410

  26. Liver metastasis is one of the most important reasons for high mortality of colorectal cancer (CRC). Growing evidence illustrates that lncRNAs play a critical role in CRC liver metastasis. Here we described a ...

    Authors: Xidi Wang, Yu Liu, Miao Zhou, Lei Yu and Zizhen Si
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:306
    Content type: Research Published on:

  27. Authors: Nianshuang Li, Yan Feng, Yi Hu, Cong He, Chuan Xie, Yaobin Ouyang, Stephen C. Artim, Deqiang Huang, Yin Zhu, Zhijun Luo, Zhongming Ge and Nonghua Lu
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:305
    Content type: Correction Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2018 37:280

  28. Diffuse pleural mesothelioma (DPM) is an aggressive therapy-resistant cancer with unique molecular features. Numerous agents have been tested, but clinically effective ones remain elusive. Herein, we propose t...

    Authors: Anand Singh, Nathanael Pruett, Shivani Dixit, Sudheer K. Gara, Haitao Wang, Roma Pahwa, David S. Schrump and Chuong D. Hoang
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:304
    Content type: Research Published on:

  29. Despite remarkable advancements in cancer immunotherapy, the overall response rate to anti-programmed cell death-1 (anti-PD-1) therapy in hepatocellular carcinoma (HCC) patients remains low. Our previous study...

    Authors: Jialiang Wang, Xiaoyu Zhang, Xinyi Ma, Dongmei Chen, Meina Cai, Lexin Xiao, Jing Li, Zexuan Huang, Yuehua Huang and Yifan Lian
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:303
    Content type: Research Published on:

  30. Understanding the mechanism behind immune cell plasticity in cancer metastasis is crucial for identifying key regulators. Previously we found that mitotic factors regulate epithelial-mesenchymal transition, bu...

    Authors: Rong Xu, Young-Joo Lee, Chang-Hyeon Kim, Ga-Hong Min, Yeo-Bin Kim, Jung-Won Park, Dae-Hoon Kim, Jung-Hyun Kim and Hyungshin Yim
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:302
    Content type: Research Published on:

  31. Inherited defects in the base-excision repair gene MBD4 predispose individuals to adenomatous polyposis and colorectal cancer, which is characterized by an accumulation of C > T transitions resulting from spon...

    Authors: Christophe Papin, Abdulkhaleg Ibrahim, Jamal S. M. Sabir, Stéphanie Le Gras, Isabelle Stoll, Raed S. Albiheyri, Ali T. Zari, Ahmed Bahieldin, Alfonso Bellacosa, Christian Bronner and Ali Hamiche
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:301
    Content type: Research Published on:

  32. Epirubicin/cyclophosphamide (EC) and docetaxel (D) are commonly used in a sequential regimen in the neoadjuvant treatment of early, high-risk or locally advanced breast cancer (BC). Novel approaches to increas...

    Authors: Kerstin Wimmer, Monika Sachet, Cristiano Ramos, Sophie Frantal, Hanna Birnleitner, Christine Brostjan, Ruth Exner, Martin Filipits, Zsuzsanna Bago-Horvath, Margaretha Rudas, Rupert Bartsch, Michael Gnant, Christian F. Singer, Marija Balic, Daniel Egle, Rudolf Oehler…
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:300
    Content type: Research Published on:

  34. Gastric-cancer is a heterogeneous type of neoplastic disease and it lacks appropriate therapeutic options. There is an urgent need for the development of innovative pharmacological strategies, particularly in ...

    Authors: Luca Guarrera, Mami Kurosaki, Silvio-Ken Garattini, Maurizio Gianni’, Gianpiero Fasola, Luca Rossit, Michele Prisciandaro, Maria Di Bartolomeo, Marco Bolis, Paola Rizzo, Claudia Nastasi, Marika Foglia, Adriana Zanetti, Gabriela Paroni, Mineko Terao and Enrico Garattini
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:298
    Content type: Research Published on:

  35. The Hippo pathway is crucial in organ size control and tumorigenesis. Dysregulation of the Hippo/YAP axis is commonly observed in gastric cancer, while effective therapeutic targets for the Hippo/YAP axis are ...

    Authors: Tianshi Wang, Dehai Wang, Yanan Sun, Ting Zhuang, Xin Li, Huijie Yang, Yifeng Zang, Ziping Liu, Penghe Yang, Chenmiao Zhang, Jiayao Cui, Mingxi Fu, Shuqing Zhang, Peng Su, Zhongbo Li, Jian Zhu…
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:297
    Content type: Research Published on:

  36. Long noncoding RNAs (lncRNAs) have been reported to play vital roles in the development and progression of cancer. However, their biological significance and functional mechanisms in non-small cell lung cancer...

    Authors: Li Zhang, Jingtian Liang, Hao Qin, Yin Lv, Xiucheng Liu, Zhuoqun Li, Zhixiang Chao, Caili Jia, Xichun Qin and Hao Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:296
    Content type: Research Published on:

  37. Ovarian cancer is commonly associated with a poor prognosis due to metastasis and chemoresistance. PINK1 (PTEN-induced kinase 1) is a serine/threonine kinase that plays a crucial part in regulating various physio...

    Authors: Fang Zheng, Jiamin Zhong, Kelie Chen, Yu Shi, Fang Wang, Shengchao Wang, Song Tang, Xiaoyu Yuan, Zhangjin Shen, Sangsang Tang, Dajing Xia, Yihua Wu and Weiguo Lu
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:295
    Content type: Research Published on:

  38. The tumor microenvironment (TME) is an important factor that regulates the progression of colorectal cancer (CRC). Cancer-associated fibroblasts (CAFs) are the main mesenchymal cells in the TME and play a vita...

    Authors: Shenghe Deng, Denglong Cheng, Jun Wang, Junnan Gu, Yifan Xue, Zhenxing Jiang, Le Qin, Fuwei Mao, Yinghao Cao and Kailin Cai
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:294
    Content type: Research Published on:

  39. Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in childhood, whose prognosis is still poor especially for metastatic, high-grade, and relapsed RMS. New treatments are urgently needed, especially...

    Authors: Andrea Timpanaro, Caroline Piccand, Dzhangar Dzhumashev, Stenija Anton-Joseph, Andrea Robbi, Janine Moser, Jochen Rössler and Michele Bernasconi
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:293
    Content type: Research Published on:

  40. Triple-negative breast cancer (TNBC) is characterized by aggressive growth and a high propensity for recurrence and metastasis. Simultaneous overexpression of c-MET and EGFR in TNBC is associated with worse cl...

    Authors: Seongjae Kim, Jung Min Park, Soeun Park, Eunsun Jung, Dongmi Ko, Minsu Park, Juyeon Seo, Kee Dal Nam, Yong Koo Kang, Kyoungmin Lee, Lee Farrand, Yoon-Jae Kim, Ji Young Kim and Jae Hong Seo
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:292
    Content type: Research Published on:

  41. Metabolic reprogramming of amino acids has been increasingly recognized to initiate and fuel tumorigenesis and survival. Therefore, there is emerging interest in the application of amino acid metabolic strateg...

    Authors: Yue Zheng, Yiran Yao, Tongxin Ge, Shengfang Ge, Renbing Jia, Xin Song and Ai Zhuang
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:291
    Content type: Review Published on:

  42. Invasion and metastasis are the main causes of unfavourable prognosis in patients diagnosed with bladder cancer. The efficacy of immunotherapy in bladder cancer remains suboptimal due to the presence of an imm...

    Authors: Wei-Min Hu, Ming Li, Jin-Zhuo Ning, Yu-Qi Tang, Tian-Bao Song, Lin-Zhi Li, Fan Zou, Fan Cheng and Wei-Min Yu
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:290
    Content type: Research Published on:

  43. TAMs (tumor-associated macrophages) infiltration promotes the progression of esophageal cancer (EC). However, the underlying mechanisms remain unclear.

    Authors: Xinwei Qiao, Zaixing Cheng, Kaming Xue, Cui Xiong, Zhikun Zheng, Xin Jin and Jinsong Li
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:289
    Content type: Research Published on:

  44. Hepatocellular carcinoma (HCC) accounts for a majority of primary liver cancer cases and related deaths. The purpose of this study was to assess the diagnostic value of splicing factor 3b subunit 4 (SF3B4) as ...

    Authors: Ju A Son, Ji Hyang Weon, Geum Ok Baek, Hye Ri Ahn, Ji Yi Choi, Moon Gyeong Yoon, Hyo Jung Cho, Jae Youn Cheong, Jung Woo Eun and Soon Sun Kim
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:288
    Content type: Research Published on:

  45. Immune checkpoint blockade (ICB) has significantly prolonged survival of non-small cell lung cancer (NSCLC) patients, although most patients develop mechanisms of resistance. Recently single-cell RNA-sequencin...

    Authors: Belinda Palermo, Ornella Franzese, Giuseppe Frisullo, Lorenzo D’Ambrosio, Mariangela Panetta, Giulia Campo, Daniel D’Andrea, Isabella Sperduti, Francesca De Nicola, Frauke Goeman, Filippo Gallina, Paolo Visca, Francesco Facciolo and Paola Nisticò
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:287
    Content type: Research Published on:

  46. The endoplasmic reticulum (ER) regulates critical processes, including lipid synthesis, which are affected by transmembrane proteins localized in the ER membrane. One such protein, transmembrane protein 147 (T...

    Authors: Jingjing Huang, Huayang Pan, Jing Sun, Jiaming Wu, Qiyue Xuan, Jinge Wang, Shanjia Ke, Shounan Lu, Zihao Li, Zhigang Feng, Yongliang Hua, Qingan Yu, Bing Yin, Baolin Qian, Menghua Zhou, Yanan Xu…
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:286
    Content type: Research Published on:

  47. Temozolomide (TMZ) treatment efficacy in glioblastoma (GBM) patients has been limited by resistance in the clinic. Currently, there are no clinically proven therapeutic options available to restore TMZ treatme...

    Authors: Shanqiang Qu, Songtao Qi, Huayang Zhang, Zhiyong Li, Kaicheng Wang, Taichen Zhu, Rongxu Ye, Wanghao Zhang, Guanglong Huang and Guo-zhong Yi
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:285
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2023 42:314

  48. Oncolytic viruses are now well recognized as potential immunotherapeutic agents against cancer. However, the first FDA-approved oncolytic herpes simplex virus 1 (HSV-1), T-VEC, showed limited benefits in some ...

    Authors: Guosong Wang, Jiali Cao, Mengxuan Gui, Pengfei Huang, Liang Zhang, Ruoyao Qi, Ruiqi Chen, Lina Lin, Qiangyuan Han, Yanhua Lin, Tian Chen, Peiqing He, Jian Ma, Rao Fu, Junping Hong, Qian Wu…
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:284
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2023 42:312

  49. Lung cancer is the most common and deadliest cancer worldwide, and approximately 90% of all lung cancer deaths are caused by tumor metastasis. Tumor-derived exosomes could potentially promote tumor metastasis ...

    Authors: Xiu-Rui Hsu, Jia-En Wu, Yi-Ying Wu, Sheng-Yen Hsiao, Jui-Lin Liang, Ya-Ju Wu, Chia-Hao Tung, Meng-Fan Huang, Ming-Shiu Lin, Pan-Chyr Yang, Yuh-Ling Chen and Tse-Ming Hong
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:283
    Content type: Research Published on:

  50. Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal cancers worldwide, mainly due to its late diagnosis and lack of effective therapies, translating into a low 5-year 12% survival rate, desp...

    Authors: Emilia Alors-Pérez, Sergio Pedraza-Arevalo, Ricardo Blázquez-Encinas, María Trinidad Moreno-Montilla, Víctor García-Vioque, Inmaculada Berbel, Raúl M. Luque, Bruno Sainz Jr, Alejandro Ibáñez-Costa and Justo P. Castaño
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:282
    Content type: Review Published on:

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Journal of Experimental & Clinical Cancer Research

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