Journal of Experimental & Clinical Cancer Research

Featured review: Emerging roles of Myc in stem cell biology and novel tumor therapies

c-Myc, N-Myc, and L-Myc are encoded by the proto-oncogene family and are essential transcription factors which belong to the superfamily of basic helix-loop-helix (bHLH) DNA-binding proteins, and are necessary for fundamental cellular activity. In this review, Go Yoshida discusses the pathophysiological roles of these three members of the Myc family, as well as their therapeutic potentials.

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Aims and scope

Journal of Experimental & Clinical Cancer Research is an online peer-reviewed journal that provides a high-quality forum for all aspects of basic, clinical and translational work in oncology.

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Editor-in-Chief

Mauro Castelli, Regina Elena National Cancer Institute, Italy

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Content type: Research
| 18 July 2019

Large oncosomes overexpressing integrin alpha-V promote prostate cancer adhesion and invasion via AKT activation

Authors: Chiara Ciardiello, Alessandra Leone, Paola Lanuti, Maria S. Roca, Tania Moccia, Valentina R. Minciacchi, Michele Minopoli, Vincenzo Gigantino, Rossella De Cecio, Massimo Rippa, Lucia Petti, Francesca Capone, Carlo Vitagliano, Maria R. Milone, Biagio Pucci, Rita Lombardi…
Content type: Research
| 18 July 2019

Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma

Authors: Ling Deng, Jingyuan Sun, Xiaohui Chen, Li Liu and Dehua Wu
Content type: Research
| 17 July 2019

ADAR1 promotes the epithelial-to-mesenchymal transition and stem-like cell phenotype of oral cancer by facilitating oncogenic microRNA maturation

Authors: Xue Liu, Yu Fu, Jiadong Huang, Meng Wu, Zhenxing Zhang, Rongyao Xu, Ping Zhang, Shouwei Zhao, Laikui Liu and Hongbing Jiang
Content type: Research
| 17 July 2019

A positive feedback between IDO1 metabolite and COL12A1 via MAPK pathway to promote gastric cancer metastasis

Authors: Zhen Xiang, Jun Li, Shuzheng Song, Jiexuan Wang, Wei Cai, Wenjun Hu, Jun Ji, Zhenggang Zhu, Lu Zang, Ranlin Yan and Yingyan Yu
Content type: Research
| 16 July 2019

HMGA1 promotes breast cancer angiogenesis supporting the stability, nuclear localization and transcriptional activity of FOXM1

Authors: Rossella Zanin, Silvia Pegoraro, Gloria Ros, Yari Ciani, Silvano Piazza, Fleur Bossi, Roberta Bulla, Cristina Zennaro, Federica Tonon, Dejan Lazarevic, Elia Stupka, Riccardo Sgarra and Guidalberto Manfioletti

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Content type: Review
| 26 September 2011

Apoptosis in cancer: from pathogenesis to treatment

Authors: Rebecca SY Wong
Content type: Review
| 6 October 2015

Metabolic reprogramming: the emerging concept and associated therapeutic strategies

Authors: Go J. Yoshida
Content type: Research
| 3 February 2016

HIF-2α promotes epithelial-mesenchymal transition through regulating Twist2 binding to the promoter of E-cadherin in pancreatic cancer

Authors: Jian Yang, Xu Zhang, Yi Zhang, Dongming Zhu, Lifeng Zhang, Ye Li, Yanbo Zhu, Dechun Li and Jian Zhou
Content type: Research
| 14 September 2009

Characterization of human breast cancer epithelial cells (HBCEC) derived from long term cultured biopsies

Authors: Ralf Hass and Catharina Bertram
Content type: Research article
| 5 February 2015

Elevated kinesin family member 26B is a prognostic biomarker and a potential therapeutic target for colorectal cancer

Authors: Jingtao Wang, Feifei Cui, Xiao Wang, Yingming Xue, Jian Chen, Yang Yu, Huijun Lu, Meng Zhang, Huamei Tang and Zhihai Peng

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Advances in Cancer Immunotherapy

Journal of Experimental & Clinical Cancer Research has published a thematic series on “Advances in Cancer Immunotherapy” to help summarize recent highlights in this field.

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Celebrating the 10th anniversary partnership with BMC

2018 marks the 10^th anniversary of the partnership between the Journal of Experimental & Clinical Cancer Research and BMC.

Over the past decade, the journal has established itself among some of the top Oncology titles in Journal Citation Reports. Click here to look back at some of the journal’s milestone achievements and best content from the past 10 years.

Reviewer Acknowledgement and New Recruitment

The Editor-in-Chief of Journal of Experimental & Clinical Cancer Research would like to thank all of our reviewers who have contributed to the journal and is looking for new reviewers to assess manuscripts. For consideration, please send your CV with keywords and expertise to jeccreditorial@gmail.com

Archival content

Journal of Experimental & Clinical Cancer Research has been publishing since 1982. Prior to publishing with BioMed Central from 2008, Journal of Experimental & Clinical Cancer Research was published in print. For enquiries about previous content, please contact us on:

jeccreditorial@gmail.com

Journal of Experimental & Clinical Cancer Research

Featured review: Emerging roles of Myc in stem cell biology and novel tumor therapies

Aims and scope

Editor-in-Chief

Articles

Large oncosomes overexpressing integrin alpha-V promote prostate cancer adhesion and invasion via AKT activation

Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma

ADAR1 promotes the epithelial-to-mesenchymal transition and stem-like cell phenotype of oral cancer by facilitating oncogenic microRNA maturation

A positive feedback between IDO1 metabolite and COL12A1 via MAPK pathway to promote gastric cancer metastasis

HMGA1 promotes breast cancer angiogenesis supporting the stability, nuclear localization and transcriptional activity of FOXM1

Apoptosis in cancer: from pathogenesis to treatment

Metabolic reprogramming: the emerging concept and associated therapeutic strategies

HIF-2α promotes epithelial-mesenchymal transition through regulating Twist2 binding to the promoter of E-cadherin in pancreatic cancer

Characterization of human breast cancer epithelial cells (HBCEC) derived from long term cultured biopsies

Elevated kinesin family member 26B is a prognostic biomarker and a potential therapeutic target for colorectal cancer

Advances in Cancer Immunotherapy

Celebrating the 10th anniversary partnership with BMC

Reviewer Acknowledgement and New Recruitment

Archival content

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