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Featured Review: The roles of tumor-derived exosomes in non-small cell lung cancer and their clinical implications

Non-small cell lung cancer (NSCLC) accounts for approximately 85% of lung cancer cases, and is one of the leading causes of cancer death in men and women worldwide due to diagnosis in the advanced stage, rapid metastasis, and recurrence. New methods are needed to develop real-time monitoring of drug efficacy and drug resistance, such as new molecular markers for more effective early detection and prediction of prognosis. 

Exosomes are nano-sized extracellular vesicles and play an important role in the development of lung cancer by controlling a wide range of pathways. Tumor-derived exosomes are of great significance for guiding the targeted therapy of NSCLC and exosomes themselves can be a target for treatment. In this review, Zheng et al. describe the potential roles of tumor-derived exosomes and their clinical significance in NSCLC.

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Aims and scope

Journal of Experimental & Clinical Cancer Research is an online peer-reviewed journal that provides a high-quality forum for all aspects of basic, clinical and translational work in oncology.

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Mauro Castelli, Regina Elena National Cancer Institute, Italy

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Advances in Cancer Immunotherapy

Advances in Cancer ImmunotherapyJournal of Experimental & Clinical Cancer Research has published a thematic series on “Advances in Cancer Immunotherapy” to help summarize recent highlights in this field. 

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Celebrating the 10th anniversary partnership with BMC

JECCR 10 years​​​​​​​2018 marks the 10th anniversary of the partnership between the Journal of Experimental & Clinical Cancer Research and BMC.

Over the past decade, the journal has established itself among some of the top Oncology titles in Journal Citation Reports. Click here to look back at some of the journal’s milestone achievements and best content from the past 10 years.

Reviewer Acknowledgement and New Recruitment

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The Editor-in-Chief of Journal of Experimental & Clinical Cancer Research would like to thank all of our reviewers who have contributed to the journal and is looking for new reviewers to assess manuscripts. For consideration, please send your CV with keywords and expertise to

Archival content

Journal of Experimental & Clinical Cancer Research has been publishing since 1982.  Prior to publishing with BioMed Central from 2008, Journal of Experimental & Clinical Cancer Research was published in print.  For enquiries about previous content, please contact us on:


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