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Featured review: Relationship between epithelial-to-mesenchymal transition and the inflammatory microenvironment of hepatocellular carcinoma

Featured Review: Relationship between EMT and the inflammatory microenvironment of HCCHepatocellular carcinoma (HCC) is the most common type of primary liver cancer. These inflammatory-related tumors are difficult to treat due to early invasion and metastasis, of which epithelial-to-mesenchymal transition (EMT) is a key step. In HCC, the inflammatory microenvironment is undoubtedly the decisive factor in tumor development, but the association between this and the occurrence of EMT is not yet clear. In this review, Long Yan et al. review the relationship between EMT and HCC's inflammatory tumor microenvironment, and elaborate on its significance.

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Aims and scope

Journal of Experimental & Clinical Cancer Research is an online peer-reviewed journal that provides a high-quality forum for all aspects of basic, clinical and translational work in oncology.

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Mauro Castelli, Regina Elena National Cancer Institute, Italy

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  1. Content type: Research


    Authors: Isabella Orienti, Valentina Salvati, Giovanni Sette, Massimo Zucchetti, Lucilla Bongiorno-Borbone, Angelo Peschiaroli, Lello Zolla, Federica Francescangeli, Mariella Ferrari, Cristina Matteo, Ezia Bello, Antonio Di Virgilio, Mario Falchi, Maria Laura De Angelis, Marta Baiocchi, Gerry Melino…

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Advances in Cancer Immunotherapy

Advances in Cancer ImmunotherapyJournal of Experimental & Clinical Cancer Research has published a thematic series on “Advances in Cancer Immunotherapy” to help summarize recent highlights in this field. 

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Celebrating the 10th anniversary partnership with BMC

JECCR 10 years​​​​​​​2018 marks the 10th anniversary of the partnership between the Journal of Experimental & Clinical Cancer Research and BMC.

Over the past decade, the journal has established itself among some of the top Oncology titles in Journal Citation Reports. Click here to look back at some of the journal’s milestone achievements and best content from the past 10 years.

Reviewer Acknowledgement and New Recruitment

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The Editor-in-Chief of Journal of Experimental & Clinical Cancer Research would like to thank all of our reviewers who have contributed to the journal and is looking for new reviewers to assess manuscripts. For consideration, please send your CV with keywords and expertise to

Archival content

Journal of Experimental & Clinical Cancer Research has been publishing since 1982.  Prior to publishing with BioMed Central from 2008, Journal of Experimental & Clinical Cancer Research was published in print.  For enquiries about previous content, please contact us on:


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