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  1. Content type: Research

    Recent studies suggested the globin family member cytoglobin (CYGB) as a potential tumor suppressor; however, the mechanism by which CYGB suppresses cancer is elusive. We investigated the role and mechanism of...

    Authors: Yixiao Feng, Mingjun Wu, Shuman Li, Xiaoqian He, Jun Tang, Weiyan Peng, Beilei Zeng, Chuxia Deng, Guosheng Ren and Tingxiu Xiang

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:313

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  2. Content type: Research

    The tetraspanins Tspan8 and CD151 promote metastasis, exosomes (Exo) being suggested to be important in the crosstalk between tumor and host. The contribution of Tspan8 and CD151 to host versus tumor-derived e...

    Authors: Kun Zhao, Zhe Wang, Thilo Hackert, Claudia Pitzer and Margot Zöller

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:312

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  3. Content type: Research

    Aldehyde dehydrogenase 1A1 (ALDH1A1), a member of aldehyde dehydrogenase family, is a marker of stemness in breast cancer. During tumor progression cancer stem cells (CSCs) have been reported to secrete angiog...

    Authors: Valerio Ciccone, Erika Terzuoli, Sandra Donnini, Antonio Giachetti, Lucia Morbidelli and Marina Ziche

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:311

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  4. Content type: Research

    Recent observations indicate a decreased cancer risk in patients with Alzheimer’s disease (AD). AD is a severe neurodegenerative disorder characterized by progressive cognitive decline. The 8q24 region has bee...

    Authors: Dan-Hua Xu, Qing Li, Hao Hu, Bo Ni, Xu Liu, Chen Huang, Zi-Zhen Zhang and Gang Zhao

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:308

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  5. Content type: Review

    Resistance to regulated cell death is one of the hallmarks of human cancers; it maintains cell survival and significantly limits the effectiveness of conventional drug therapy. Leukemia represents a class of h...

    Authors: Xianbo Huang, Feng Xiao, Yuan Li, Wenbin Qian, Wei Ding and Xiujin Ye

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:310

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  6. Content type: Research

    Prostate cancer is one of the most commonly diagnosed cancers in men worldwide. Currently available therapies for metastatic prostate cancer are only marginally effective. Therefore, new therapeutic agents are...

    Authors: Wei Chen, Ping Li, Yi Liu, Yu Yang, Xueting Ye, Fangyi Zhang and Hang Huang

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:309

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  7. Content type: Research

    The peritoneum is one of the most frequent metastatic sites in pancreatic cancer patients, and peritoneal dissemination makes this disease refractory due to aggressive progression and chemoresistance. Although...

    Authors: Kazuya Kuwada, Shunsuke Kagawa, Ryuichi Yoshida, Shuichi Sakamoto, Atene Ito, Megumi Watanabe, Takeshi Ieda, Shinji Kuroda, Satoru Kikuchi, Hiroshi Tazawa and Toshiyoshi Fujiwara

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:307

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  8. Content type: Research

    There has been no satisfactory treatment for advanced melanoma until now. Targeted radionuclide therapy (TRNT) may be a promising option for this heretofore lethal disease. Our goal in this study was to synthe...

    Authors: Xiaodong Xu, Lujie Yuan, Yongkang Gai, Qingyao Liu, Lianglan Yin, Yaqun Jiang, Yichun Wang, Yongxue Zhang and Xiaoli Lan

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:306

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  9. Content type: Research

    Inosine 5′-monophosphate dehydrogenase type II (IMPDH2) was originally identified as an oncogene in several human cancers. However, the clinical significance and biological role of IMPDH2 remain poorly underst...

    Authors: Shiyu Duan, Wenqing Huang, Xiaoting Liu, Xuming Liu, Nana Chen, Qiong Xu, Yukun Hu, Wen Song and Jun Zhou

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:304

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  10. Content type: Research

    We and others have previously shown that the STAT3 signaling pathway is activated in some esophageal squamous cell carcinoma (ESCC) cells and is required for the survival and growth of these primary ESCC-deriv...

    Authors: Ying Liu, Xinhua Wang, Shuang Zeng, Xiane Zhang, Jimin Zhao, Xiaoyan Zhang, Xinhuan Chen, Wanjing Yang, Yili Yang, Ziming Dong, Jingyu Zhu, Xin Xu and Fang Tian

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:303

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  11. Content type: Research

    Cancer stem cells (CSCs) possess abilities of self-renewal and differentiation, have oncogenic potential and are regarded to be the source of cancer recurrence. However, the mechanism by which CSCs maintain th...

    Authors: Shanshan Xu, Yongfang Yue, Songfa Zhang, Caiyun Zhou, Xiaodong Cheng, Xing Xie, Xinyu Wang and Weiguo Lu

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:305

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  12. Content type: Research

    Non–small-cell lung cancer (NSCLC) is a heterogeneous disease, with multiple different oncogenic mutations. Approximately 25–30% of NSCLC patients present KRAS mutations, which confer poor prognosis and high r...

    Authors: Elisa Caiola, Francesca Falcetta, Silvia Giordano, Mirko Marabese, Marina C. Garassino, Massimo Broggini, Roberta Pastorelli and Laura Brunelli

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:302

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  13. Content type: Research

    Esophageal cancer is a high incident cancer worldwide with poor survival and limited therapeutic options. Alterations of microRNAs are common in cancers, and many of these micro RNAs are potential therapeutic ...

    Authors: Yi-fang Lu, Jia-rui Yu, Zhao Yang, Guan-xia Zhu, Peng Gao, Huan Wang, Si-yuan Chen, Jie Zhang, Mei-yue Liu, Yi Niu, Xiao-mei Wei, Wei Wang, Feng-jin Ye, Li-xin Zhang, Yue Zhao and Guo-gui Sun

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:301

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  14. Content type: Research

    RNA binding proteins (RBPs) play an important role in regulating the metabolism of target RNAs. Aberrant expression of RBPs plays a vital role in the initiation and development of many cancers. The RBM family,...

    Authors: Xi Sun, Yue Hu, Jing Wu, Liang Shi, Lei Zhu, Pei-Wen Xi, Ji-Fu Wei and Qiang Ding

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:298

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  15. Content type: Research

    Colorectal cancer (CRC) is one of the most common digestive malignant tumors, and DMTN is a transcriptionally differentially expressed gene that was identified using CRC mRNA sequencing data from The Cancer Ge...

    Authors: Ya-Ping Ye, Hong-Li Jiao, Shu-Yang Wang, Zhi-Yuan Xiao, Dan Zhang, Jun-Feng Qiu, Ling-Jie Zhang, Ya-Li Zhao, Ting-Ting Li, Li-Liang, Wen-Ting Liao and Yan-Qing Ding

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:299

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  16. Content type: Research

    Previous evidence demonstrated that restoration of wild type VHL in human renal cancer cells decreased in vitro NK susceptibility. To investigate on the role of tumoral VHL status versus NK capability in renal...

    Authors: Anna Maria Trotta, Sara Santagata, Serena Zanotta, Crescenzo D’Alterio, Maria Napolitano, Giuseppina Rea, Rosa Camerlingo, Fabio Esposito, Elvira Lamantia, Annamaria Anniciello, Giovanni Botti, Nicola Longo, Gerardo Botti, Sandro Pignata, Sisto Perdonà and Stefania Scala

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:297

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  17. Content type: Research

    Numerous studies have demonstrated that tetraspanin 1 (TSPAN1), a transmembrane protein, functions as an oncoprotein in many cancer types. However, its role and underlying molecular mechanism in cholangiocarci...

    Authors: Yan Wang, Yingjian Liang, Guangchao Yang, Yaliang Lan, Jihua Han, Jiabei Wang, Dalong Yin, Ruipeng Song, Tongsen Zheng, Shugeng Zhang, Shangha Pan, Xirui Liu, Mingxi Zhu, Yao Liu, Yifeng Cui, Fanzheng Meng…

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:300

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  18. Content type: Research

    Cancer stem cells (CSCs) play a key role in cancer initiation, progression and chemoresistance. Epigenetic alterations have been identified as prominent factors that contribute to the CSCs phenotype. Here, we ...

    Authors: Marcella La Noce, Francesca Paino, Luigi Mele, Gianpaolo Papaccio, Tarik Regad, Angela Lombardi, Federica Papaccio, Vincenzo Desiderio and Virginia Tirino

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:296

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  19. Content type: Research

    Accumulation of evidence indicates that miRNAs have crucial roles in the regulation of EMT-associated properties, such as proliferation, migration and invasion. However, the underlying molecular mechanisms are...

    Authors: Dong-Min Shi, Li-Xin Li, Xin-Yu Bian, Xue-Jiang Shi, Li-Li Lu, Hong-Xin Zhou, Ting-Jia Pan, Jian Zhou, Jia Fan and Wei-Zhong Wu

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:294

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  20. Content type: Research

    Ligand-dependent activation of the G-protein coupled receptor 119 (GPR119) lowers blood glucose via glucose-dependent insulin secretion and intestinal glucagon-like peptide-1 production. However, the function ...

    Authors: Ji Hye Im, Keon Wook Kang, Sun Young Kim, Yoon Gyoon Kim, Yong Jin An, Sunghyouk Park, Byung Hwa Jeong, Song-Yi Choi, Jin-Sun Lee and Keon Wook Kang

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:295

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  21. Content type: Research

    Transcription factor forkhead box M1 (FOXM1) is a crucial regulator in colorectal cancer (CRC) progression. However, the regulatory mechanisms causing dysregulation of FOXM1 in CRC remain unclear.

    Authors: Ye Wang, Meijuan Wu, Zengjie Lei, Mengxi Huang, Zhiping Li, Liya Wang, Qijun Cao, Dong Han, Yue Chang, Yanyan Chen, Xiaobei Liu, Lijun Xue, Xiaobei Mao, Jian Geng, Yanan Chen, Tingting Dai…

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:292

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  22. Content type: Research

    Profound chemoresistance remains an intractable obstacle in pancreatic cancer treatment. Pancreatic cancer stem cells (CSCs) and the ubiquitous hypoxic niche have been proposed to account for drug resistance. ...

    Authors: Zhengle Zhang, Han Han, Yuping Rong, Kongfan Zhu, Zhongchao Zhu, Zhigang Tang, Chenglong Xiong and Jing Tao

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:291

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  23. Content type: Research

    Interleukin-32 (IL-32) has been associated with various diseases. Previous studies have shown that IL-32 inhibited the development of several tumors. However, the role of IL-32γ, an isotype of IL-32, in skin c...

    Authors: Yong Sun Lee, Chung Hee Lee, Jun Tae Bae, Kyung Tak Nam, Dae Bong Moon, Ok Kyung Hwang, Jeong Soon Choi, Tae Hoon Kim, Hyoung Ok Jun, Young Suk Jung, Dae Yeon Hwang, Sang-Bae Han, Do Young Yoon and Jin Tae Hong

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:293

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  24. Content type: Research

    Hepatocellular carcinoma (HCC) is the most common type of liver cancer with increasing incidence and poor prognosis. Ubiquitination regulators are reported to play crucial roles in HCC carcinogenesis. UBE2D1, ...

    Authors: Chuanchuan Zhou, Fengrui Bi, Jihang Yuan, Fu Yang and Shuhan Sun

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:290

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  25. Content type: Research

    Recent studies have indicated that deubiquitinating enzymes (DUBs) are related to the stem-cell pathway network and chemo-resistance in cancer. Ubiquitin-specific peptidase 37 (USP37), a novel DUB, was identif...

    Authors: Tao Qin, Bai Li, Xiaoyue Feng, Shujun Fan, Lei Liu, Dandan Liu, Jun Mao, Ying Lu, Jinfeng Yang, Xiaotang Yu, Qingqing Zhang, Jun Zhang, Bo Song, Man Li and Lianhong Li

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:287

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  26. Content type: Research

    Triple negative breast cancer (TNBC) easily develops resistance to the first-line drug doxorubicin, because of the high levels of the drug efflux transporter P-glycoprotein (Pgp) and the activation of pro-surv...

    Authors: Iris C. Salaroglio, Elena Gazzano, Ahmad Abdullrahman, Eleonora Mungo, Barbara Castella, Gamal Eldein Fathy Abd-ellatef Abd-elrahman, Massimo Massaia, Massimo Donadelli, Menachem Rubinstein, Chiara Riganti and Joanna Kopecka

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:286

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  27. Content type: Research

    Drugs that inhibit the MEK/ERK pathway have therapeutic benefit in bladder cancer treatment but responses vary with patients, for reasons that are still not very clear. Interferon-α (IFN-α) is also used as a t...

    Authors: Zhe Qiang, Zong-yuan Zhou, Ting Peng, Pu-zi Jiang, Nan Shi, Emmanuel Mfotie Njoya, Bahtigul Azimova, Wan-li Liu, Wei-hua Chen, Guo-lin Zhang and Fei Wang

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:288

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  28. Content type: Research

    Emerging evidence have illustrated the vital role of long noncoding RNAs (lncRNAs) long intergenic non-protein coding RNA 00511 (LINC00511) on the human cancer progression and tumorigenesis. However, the role ...

    Authors: Guanming Lu, Yueyong Li, Yanfei Ma, Jinlan Lu, Yongcheng Chen, Qiulan Jiang, Qiang Qin, Lifeng Zhao, Qianfang Huang, Zhizhai Luo, Shiqing Huang and Zhongheng Wei

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:289

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  30. Content type: Research

    MNAT1 (menage a trois 1, MAT1), a cyclin-dependent kinase-activating kinase (CAK) complex, high expresses in various cancers and is involved in cancer pathogenesis. However, mechanisms underlying its regulatio...

    Authors: Shan Zhou, Jinping Lu, Yuejin Li, Chan Chen, Yongqiang Cai, Gongjun Tan, Zhengke Peng, Zhenlin Zhang, Zigang Dong, Tiebang Kang and Faqing Tang

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:284

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  31. Content type: Research

    Cancer-associated fibroblasts (CAFs) are activated fibroblasts associated with cancer. They have an important role in tumor growth and metastasis. Artemisinin (ART) is a sesquiterpene lactone extracted from Ch...

    Authors: Yuyuan Yao, Qinglong Guo, Yue Cao, Yangmin Qiu, Renxiang Tan, Zhou Yu, Yuxin Zhou and Na Lu

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:282

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  32. Content type: Research

    Epstein-Barr virus (EBV) is ubiquitously associated with nasopharyngeal carcinoma (NPC). EBV encodes two groups of microRNAs (miRNAs) which are divided into BamHI fragment H rightward open reading frame 1 (BHRF1)...

    Authors: Cheng Lin, Jingfeng Zong, Wansong Lin, Minghui Wang, Yuanji Xu, Rui Zhou, Shaojun Lin, Qiaojuan Guo, Honglin Chen, Yunbin Ye, Bin Zhang and Jianji Pan

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:283

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  33. Content type: Research

    Kindlin-1, − 2, and − 3 are the three members of the Kindlin family. They are best known as regulators of integrin functions, contributing to fundamental biological processes such as cell survival, adhesion an...

    Authors: Paula Azorin, Florian Bonin, Ahmad Moukachar, Aurélie Ponceau, Sophie Vacher, Ivan Bièche, Elisabetta Marangoni, Laetitia Fuhrmann, Anne Vincent-Salomon, Rosette Lidereau and Keltouma Driouch

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:281

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  34. Content type: Research

    Helicobacter pylori (H. pylori) delivers oncoprotein CagA into gastric epithelial cells via the T4SS and drives activation of multiple oncogenic signalling pathways. YAP, a core effector of the Hippo tumour suppr...

    Authors: Nianshuang Li, Yan Feng, Yi Hu, Cong He, Chuan Xie, Yaobin Ouyang, Stephen C. Artim, Deqiang Huang, Yin Zhu, Zhijun Luo, Zhongming Ge and Nonghua Lu

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:280

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  35. Content type: Research

    Thyroid cancer is one of the most prevalent malignancies in endocrine system. Further understanding and revealing the molecular mechanism underlying thyroid cancer are indispensable for the development of effe...

    Authors: Hua Liu, Haoyu Deng, Yajie Zhao, Can Li and Yu Liang

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:279

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  36. Content type: Research

    Melanoma, the most aggressive form of skin cancer, is characterized by high rates of metastasis, drug resistance and mortality. Here we investigated the role of Semaphorin 5A (Sema5A) on the properties associa...

    Authors: Simona D’Aguanno, Elisabetta Valentini, Maria Grazia Tupone, Marianna Desideri, Marta Di Martile, Manuela Spagnuolo, Simonetta Buglioni, Cristiana Ercolani, Italia Falcone, Marco De Dominici, Michele Milella, Maria Giulia Rizzo, Bruno Calabretta, Carlo Cota, Andrea Anichini, Daniela Trisciuoglio…

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:278

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  37. Content type: Research

    The increase in the levels of reactive oxygen species (ROS) in acute myeloid leukemia (AML) patients has been previously described; thus, it is important to regulate ROS levels in AML.

    Authors: Yanxia Jin, Qian Yang, Li Liang, Lu Ding, Yuxing Liang, Dongdong Zhang, Balu Wu, Tian Yang, Hailing Liu, Tingting Huang, Hui Shen, Honglei Tu, Yunbao Pan, Yongchang Wei, Yi Yang and Fuling Zhou

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:277

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  38. Content type: Research

    Metastasis is the primary cause of death in renal cell carcinoma (RCC). Loss of cell-to-cell adhesion, including tight junctions (TJs) is the initial step in the process of metastasis. Claudin-7 (CLDN7) is a m...

    Authors: Yifan Li, Yanqing Gong, Xianghui Ning, Ding Peng, Libo Liu, Shiming He, Kan Gong, Cuijian Zhang, Xuesong Li and Liqun Zhou

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:276

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  39. Content type: Research

    As a type of recently discovered noncoding RNA, circular RNAs (circRNAs) exert pivot biological functions in diverse cancers. However, the role of circRNA_102171 in papillary thyroid cancer (PTC) has not been ...

    Authors: Wen Bi, Jiayu Huang, Chunlei Nie, Bo Liu, Guoqing He, Jihua Han, Rui Pang, Zhaoming Ding, Jin Xu and Jiewu Zhang

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:275

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  40. Content type: Research

    Reprogrammed energy metabolism has become an emerging hallmark of cancer in recent years. Transporters have been reported to be amino acid sensors involved in controlling mTOR recruitment and activation, which...

    Authors: Mengyu Feng, Guangbing Xiong, Zhe Cao, Gang Yang, Suli Zheng, Jiangdong Qiu, Lei You, Lianfang Zheng, Taiping Zhang and Yupei Zhao

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:274

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  41. Content type: Research

    Accumulating evidences have indicated that long non-coding RNAs (lncRNAs) are potential biomarkers that play key roles in tumor development and progression. Differentiation antagonizing non-protein noding RNA ...

    Authors: Yonghao Zhan, Zhicong Chen, Yifan Li, Anbang He, Shiming He, Yanqing Gong, Xuesong Li and Liqun Zhou

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:273

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  42. Content type: Research

    Multidrug resistance remains a major obstacle to successful treatment for patients with gastric cancer (GC). Recently, glycosylation has been demonstrated to play a vital role in the acquisition of multidrug r...

    Authors: Jian Wu, Sheng Chen, Hao Liu, Zhe Zhang, Zhen Ni, Jie Chen, Zhiping Yang, Yongzhan Nie and Daiming Fan

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:272

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  43. Content type: Research

    Bioenergetic characterisation of malignant tissues revealed that different tumour cells can catabolise multiple substrates as salvage pathways, in response to metabolic stress. Altered metabolism in gliomas ha...

    Authors: Zoltán Hujber, Gergő Horváth, Gábor Petővári, Ildikó Krencz, Titanilla Dankó, Katalin Mészáros, Hajnalka Rajnai, Norbert Szoboszlai, William P. J. Leenders, András Jeney, László Tretter and Anna Sebestyén

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:271

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  44. Content type: Correction

    In the publication of this article [1], there are two inadvertent errors.

    Authors: Wuhua Zhou, Li Gong, Qinchuan Wu, Chunyang Xing, Bajin Wei, Tianchi Chen, Yuan Zhou, Shengyong Yin, Bin Jiang, Haiyang Xie, Lin Zhou and Shusen Zheng

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:270

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    The original article was published in Journal of Experimental & Clinical Cancer Research 2018 37:215

  45. Content type: Research

    Vitex negundo L (Verbenaceae) is an aromatic shrub that is abundant in Asian countries. A series of compounds from Vitex negundo have been used in traditional Chinese medicine for the treatment of various disease...

    Authors: Nian Liu, Kuan Song Wang, Min Qi, Ying Jun Zhou, Guang Yao Zeng, Juan Tao, Jian Da Zhou, Jiang Lin Zhang, Xiang Chen and Cong Peng

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:269

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  46. Content type: Research

    MicroRNAs (miRNAs) posttranscriptionally regulate gene expression and thereby contribute to the modulation of numerous complex and disease-relevant cellular processes, including cell proliferation, cell motili...

    Authors: Ke-ting Que, Yun Zhou, Yu You, Zhen Zhang, Xiao-ping Zhao, Jian-ping Gong and Zuo-jin Liu

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:268

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  47. Content type: Correction

    In the publication of this article (1), there is an error in Fig. 5b. This has now been updated in the original article (1).

    Authors: Zeribe C. Nwosu, Nadia Battello, Melanie Rothley, Weronika Piorońska, Barbara Sitek, Matthias P. Ebert, Ute Hofmann, Jonathan Sleeman, Stefan Wölfl, Christoph Meyer, Dominik A. Megger and Steven Dooley

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:267

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    The original article was published in Journal of Experimental & Clinical Cancer Research 2018 37:211

  48. Content type: Review

    Most chemotherapeutics elevate intracellular levels of reactive oxygen species (ROS), and many can alter redox-homeostasis of cancer cells. It is widely accepted that the anticancer effect of these chemotherap...

    Authors: Haotian Yang, Rehan M Villani, Haolu Wang, Matthew J Simpson, Michael S Roberts, Min Tang and Xiaowen Liang

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:266

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  49. Content type: Research

    Human carbonyl reductase 1 (CBR1) plays major roles in protecting cells against cellular damage resulting from oxidative stress. Although CBR1-mediated detoxification of oxidative materials increased by stress...

    Authors: Miyong Yun, Ae Jin Choi, Young Chan Lee, Munkyoo Kong, Ji-Youn Sung, Sung Soo Kim and Young-Gyu Eun

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:264

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  50. Content type: Commentary

    This commentary wishes to highlight the 2018 Nobel Prize in Medicine awarded to two cancer immunotherapy scientists, Prof James Allison and Prof Tasuku Honjo, for their discovery on unleashing the body’s immun...

    Authors: Anand Rotte, Gabriella D’Orazi and Madhuri Bhandaru

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:262

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