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Table 10 A list of quality of life studies covering supportive care topics in breast cancer patients (1974–2007)

From: Health-related quality of life in breast cancer patients: A bibliographic review of the literature from 1974 to 2007

Author (s) [Ref.] Year Intervention Results/conclusion(s)
van Holten-Verzantvoort et al. [217] 1991 Pamidronate vs. control to reduce skeletal morbidity Less short-term mobility impairment and bone pain in treatment group but not at long term.
Young-McCaughan and Sexton [218] 1991 Aerobic exercise Higher QOL in women who exercised.
Soukop et al. [219] 1992 Ondansetron vs. metoclopramide to control emesis Ondansetron was significantly superior.
Kornblith et al. [220] 1993 Megestrol acetate in dose-response trial to prevent appetite loss Lower dose was optimal achieving fewest side effects and a better QOL.
Clavel et al. [221] 1993 Ondansetron to control emesis (review of five randomized trials) Ondansetron provided significant QOL benefits compared with metoclopramide and alizapride)
Ashbury et al. [222] 1998 One-on-one peer support (Reach to Recovery programme) Patients were satisfied and the programme had incremental benefits to QOL of patients.
Lee [223] 1997 Social support (Reach to Recovery programme) Social support plays a vital role in promoting overall QOL.
Wengstrom et al. [224] 1999 Nursing intervention vs. control No measurable effect on side effects or QOL but proved to have a positive effect in minimizing stress.
Lachaine et al. [225] 1999 Ondansetron or metoclopramide to control emesis Emesis control was significantly better in ondansetron; global QOL decreased more with metoclopramide.
Ritz et al. [226] 2000 Advanced nursing care (APN)+ standard care vs. standard care APN improved some QOL indicators.
Molenaar et al. [227] 2001 Decision support to help patients to choose mastectomy or breast conservation Decision-making improved as evaluated in terms of satisfaction and QOL.
Sammarco [228] 2001 Perceived social support and uncertainty in younger breast cancer survivors Significant positive correlation between perceived social support and QOL, and significant negative correlation between uncertainty, and QOL.
Michael et al. [229] 2002 Social networks Pre-diagnosis level of social integration was important factor in future QOL, and explains more of the variance than treatment or tumour characteristics.
Olsson et al. [230] 2002 Erythropoietin (randomized to two different doses epoetin-beta) for treatment of anemia Global QOL was significantly improved and there was no difference between two study arms.
O'Shaughnessy [231] 2002 Effects of epoetin-alfa to prevent neuronal apoptosis vs. placebo Improved cognitive function, mood and QOL in treatment group.
Graves et al. [232] 2003 8-week intervention based on social cognitive theory vs. standard care Women in intervention group improved more on QOL, mood, self-efficacy, and outcome expectations.
Courneya et al. [233] 2003 Exercise training (randomized trial) Exercise training had beneficial effects on QOL.
Turner [234] 2004 Seated exercise Reduced fatigue and improved QOL observed.
Headley et al. [235] 2004 Effect of seated exercise vs. control Women with advanced breast cancer randomized to the seated exercise had a slower decline in total physical well-being and less increase in fatigue.
Weinfurt et al. [236] 2004 Zoledronic asid or pamidornate disodium for metastatic bone lesion Overall increase in QOL was observed.
Diel et al. [237] 2004 Ibandronate vs. placebo in breast cancer with metastatic bone pain A significant improvement in QOL was observed in intervention group; fatigue and pain were also reduced.
Body et al. [238] 2004 Ibandronate vs. placebo in breast cancer with metastatic bone pain Oral ibandronate had beneficial effects on bone pain and QOL and was well tolerated.
Wardley et al. [239] 2005 Zoledronic acid in community setting vs. hospital setting in breast cancer patients with bone metastases No difference between settings; safety and QOL benefits were observed.
Yoo et al. [240] 2005 Muscle relaxation training and guided imagery vs. control Less anticipatory and post-chemotherapy nausea and vomiting and higher QOL in intervention group.
Manning-Walsh [241] 2005 Relationships between persona land religious support and symptom distress and QOL Personal support was positively related to QOL and had partial mediated effects on symptom distress but religious support was not.
Gordon et al. [242] 2005 Home-based physiotherapy or group-based exercise or no intervention Physiotherapy was found beneficial for functioning, physical and overall QOL.
Kendall et al. [243] 2005 Influence of exercise (13.2 years following diagnosis) High level of functioning was observed; those whose exercise increased, maintained a better QOL.
Chang et al. [244] 2005 Effect of weekly epoetin alfa on maintaining hemoglobin levels, and reduction of transfusion vs. standard care Epoetin alfa improved QOL, maintained hemoglobin levels and reduced of transfusion.
Hudis et al [245] 2005 Effect of weekly epoetin alfa on hemoglobin levels Epoetin alfa improved hemoglobin levels, and QOL in mildly anemic patients.
Badger et al. [246] 2005 Telephone interpersonal counseling (TPC) vs. usual care TIP-C was partially effective in symptom management and improved QOL.
Cheema and Gual [247] 2006 Full-body exercise training (before and after evaluation study) Significant improvements were observed in upper- and lower-body strength, endurance, and QOL.
Sutton and Erlen [248] 2006 Mutual dyadic support intervention Most dyadic relationships were supportive, some reciprocal and some experienced conflicts.
Round et al. [249] 2006 Recovery advice to prevent treatment problems Recovery advice given to women neither was supported nor refuted to be able improve QOL.
Giese-Davis et al. [250] 2006 Peer counseling intervention (newly diagnosed and peer counselors) Significant improvement in newly diagnosed was observed in trauma symptoms, emotional well-being, and self-efficacy but increased emotional suppression and declined QOL in peer counselors.
Moadel et al. [251] 2007 Effects of yoga on QOL Yoga was associated with beneficial effects on social functioning among breast cancer survivors.
Hartmann et al. [252] 2007 Effects of a step-by-step inpatient rehabilitation programme and QOL Although not generally superior to conventional inpatient rehabilitation programmes, the step-by-step rehabilitation provided marked benefits for patients with cognitive impairments.
Kim et al. [253] 2007 Effect of complex decongestive therapy (CDT) on edema and QOL in breast cancer patients with unilateral leymphedema CDT for upper limb lymphedema resulted in significant improved edema and QOL.