Table 10 A list of quality of life studies covering supportive care topics in breast cancer patients (1974–2007)
Author (s) [Ref.] | Year | Intervention | Results/conclusion(s) |
|---|---|---|---|
van Holten-Verzantvoort et al. [217] | 1991 | Pamidronate vs. control to reduce skeletal morbidity | Less short-term mobility impairment and bone pain in treatment group but not at long term. |
Young-McCaughan and Sexton [218] | 1991 | Aerobic exercise | Higher QOL in women who exercised. |
Soukop et al. [219] | 1992 | Ondansetron vs. metoclopramide to control emesis | Ondansetron was significantly superior. |
Kornblith et al. [220] | 1993 | Megestrol acetate in dose-response trial to prevent appetite loss | Lower dose was optimal achieving fewest side effects and a better QOL. |
Clavel et al. [221] | 1993 | Ondansetron to control emesis (review of five randomized trials) | Ondansetron provided significant QOL benefits compared with metoclopramide and alizapride) |
Ashbury et al. [222] | 1998 | One-on-one peer support (Reach to Recovery programme) | Patients were satisfied and the programme had incremental benefits to QOL of patients. |
Lee [223] | 1997 | Social support (Reach to Recovery programme) | Social support plays a vital role in promoting overall QOL. |
Wengstrom et al. [224] | 1999 | Nursing intervention vs. control | No measurable effect on side effects or QOL but proved to have a positive effect in minimizing stress. |
Lachaine et al. [225] | 1999 | Ondansetron or metoclopramide to control emesis | Emesis control was significantly better in ondansetron; global QOL decreased more with metoclopramide. |
Ritz et al. [226] | 2000 | Advanced nursing care (APN)+ standard care vs. standard care | APN improved some QOL indicators. |
Molenaar et al. [227] | 2001 | Decision support to help patients to choose mastectomy or breast conservation | Decision-making improved as evaluated in terms of satisfaction and QOL. |
Sammarco [228] | 2001 | Perceived social support and uncertainty in younger breast cancer survivors | Significant positive correlation between perceived social support and QOL, and significant negative correlation between uncertainty, and QOL. |
Michael et al. [229] | 2002 | Social networks | Pre-diagnosis level of social integration was important factor in future QOL, and explains more of the variance than treatment or tumour characteristics. |
Olsson et al. [230] | 2002 | Erythropoietin (randomized to two different doses epoetin-beta) for treatment of anemia | Global QOL was significantly improved and there was no difference between two study arms. |
O'Shaughnessy [231] | 2002 | Effects of epoetin-alfa to prevent neuronal apoptosis vs. placebo | Improved cognitive function, mood and QOL in treatment group. |
Graves et al. [232] | 2003 | 8-week intervention based on social cognitive theory vs. standard care | Women in intervention group improved more on QOL, mood, self-efficacy, and outcome expectations. |
Courneya et al. [233] | 2003 | Exercise training (randomized trial) | Exercise training had beneficial effects on QOL. |
Turner [234] | 2004 | Seated exercise | Reduced fatigue and improved QOL observed. |
Headley et al. [235] | 2004 | Effect of seated exercise vs. control | Women with advanced breast cancer randomized to the seated exercise had a slower decline in total physical well-being and less increase in fatigue. |
Weinfurt et al. [236] | 2004 | Zoledronic asid or pamidornate disodium for metastatic bone lesion | Overall increase in QOL was observed. |
Diel et al. [237] | 2004 | Ibandronate vs. placebo in breast cancer with metastatic bone pain | A significant improvement in QOL was observed in intervention group; fatigue and pain were also reduced. |
Body et al. [238] | 2004 | Ibandronate vs. placebo in breast cancer with metastatic bone pain | Oral ibandronate had beneficial effects on bone pain and QOL and was well tolerated. |
Wardley et al. [239] | 2005 | Zoledronic acid in community setting vs. hospital setting in breast cancer patients with bone metastases | No difference between settings; safety and QOL benefits were observed. |
Yoo et al. [240] | 2005 | Muscle relaxation training and guided imagery vs. control | Less anticipatory and post-chemotherapy nausea and vomiting and higher QOL in intervention group. |
Manning-Walsh [241] | 2005 | Relationships between persona land religious support and symptom distress and QOL | Personal support was positively related to QOL and had partial mediated effects on symptom distress but religious support was not. |
Gordon et al. [242] | 2005 | Home-based physiotherapy or group-based exercise or no intervention | Physiotherapy was found beneficial for functioning, physical and overall QOL. |
Kendall et al. [243] | 2005 | Influence of exercise (13.2 years following diagnosis) | High level of functioning was observed; those whose exercise increased, maintained a better QOL. |
Chang et al. [244] | 2005 | Effect of weekly epoetin alfa on maintaining hemoglobin levels, and reduction of transfusion vs. standard care | Epoetin alfa improved QOL, maintained hemoglobin levels and reduced of transfusion. |
Hudis et al [245] | 2005 | Effect of weekly epoetin alfa on hemoglobin levels | Epoetin alfa improved hemoglobin levels, and QOL in mildly anemic patients. |
Badger et al. [246] | 2005 | Telephone interpersonal counseling (TPC) vs. usual care | TIP-C was partially effective in symptom management and improved QOL. |
Cheema and Gual [247] | 2006 | Full-body exercise training (before and after evaluation study) | Significant improvements were observed in upper- and lower-body strength, endurance, and QOL. |
Sutton and Erlen [248] | 2006 | Mutual dyadic support intervention | Most dyadic relationships were supportive, some reciprocal and some experienced conflicts. |
Round et al. [249] | 2006 | Recovery advice to prevent treatment problems | Recovery advice given to women neither was supported nor refuted to be able improve QOL. |
Giese-Davis et al. [250] | 2006 | Peer counseling intervention (newly diagnosed and peer counselors) | Significant improvement in newly diagnosed was observed in trauma symptoms, emotional well-being, and self-efficacy but increased emotional suppression and declined QOL in peer counselors. |
Moadel et al. [251] | 2007 | Effects of yoga on QOL | Yoga was associated with beneficial effects on social functioning among breast cancer survivors. |
Hartmann et al. [252] | 2007 | Effects of a step-by-step inpatient rehabilitation programme and QOL | Although not generally superior to conventional inpatient rehabilitation programmes, the step-by-step rehabilitation provided marked benefits for patients with cognitive impairments. |
Kim et al. [253] | 2007 | Effect of complex decongestive therapy (CDT) on edema and QOL in breast cancer patients with unilateral leymphedema | CDT for upper limb lymphedema resulted in significant improved edema and QOL. |