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Table 2 Genes in networks

From: Gene expression subtraction of non-cancerous lung from smokers and non-smokers with adenocarcinoma, as a predictor for smokers developing lung cancer

Network Genes in Network Score Focus Genes Top function
1 AIP, ATF2, BTK, CASBAP2, CD44, EEF1A1, EGR1, EP300, EPHA2, TF21, HMGB1, HSPA8, HSPCB, IRF2, IRS4, KIAA0853, LEPR, MAP2K3, NFYB, NPM1, NR3C1, P8, PCTK2, PECAM1, PSME3, PTPN11, RDX, SNX2, STAT*, TGFBR2, TNFRSF6, YWHAZ*, YY1 51 35 Cell death, Cancer, Inflammatory diseases
2 CCT2, CD3Z, CDK2, COL6A1, COL6A2, COL6A3, EIF5, EWSR1, FCGR3B, FGF2, FGFBP1, FMR1, FUSIP1, GNA11, GNA13, GNB1, INPP5E, M11S1*, MAPKAP1, Pkci, PPR1R12A, PRKCZ, RAI14, RBM4, RGS13, RMOQ, SFN*, SKP1A, SQSTM1, STX4A, SYPL, UBE2A, VAMP2, VAPA, YWHAG 26 31 Cellular assembly and organization, Cellular function and maintenance, Cell signaling
3 ATF2, C19orf2, DHX9, DR1, RBLN1, FHL1*, FN1, HBA1, HBA2, HBB*, HBE1, HBG1, HBG2, HBZ, HHEX, HMGB1, HNRPA1, HNRPC, IL6, LRPPRC, MTPN, NRP1, PAPOLA, POLR2A, POLR2F, RBPSUH, REL, RNU2, RPS25, SMARCB1, SNAPC2, TBP, TCF21, TNXB, VEGFB 18 19 Cell to cell signaling and interaction. Cell morphology.
4 ADAB1*, AK2, ALCAM, AQP1, CDC2, CDKN2A, CLU, CDP, FOS, GD12, MIF, MYBL2, MYC, MYCN, PRDX1, PRDX2, PRKACB, PRKARIB, RBMS1, RPL7A, RPS16, SUMO2, TPM1, TXN, UNR 15 15 Cellular growth and proliferation, cellular and connective tissue development
5 CCL20, CD44, CDC2, CEPBP, CXCL1, FOS, G3BP2, ICAM1, KIAA0992, MCF2, MET, MGAT4A, MTPN, NFKB1, NFKB1B, NR3C1, OK/SW-cl.56, PSMA7, RDX, RELA, RHOC, RPS24, SCAMP1, SMARCA4, SNAP23, STAT1*, STX4A, STX6, TLR2, TNF, TRA1*, TUBA6, VAMP3*, VIL2, WASF2 15 17 Cell death, Immunological disease
6 ALDH1A1, ANXA2, BRAF, BRCA1, CCNB1, CDK4, CDKN2A, DDA3, DHX9, HMGA1, IDI1, IPO7, KPNA4, KPNB1, LMO4, MMP2, MYCN, MMI, NPM1, RASGRP1, RBBPS, RPL12, RPL19, RPL23A, RPL3, RPL31, RPL37A, RPL39, RPL5, RPLPO, RPS2, SFN*, TBX2*, TP73, TP73L 15 17 Cancer, Cell morphology, Cellular development
  1. Genes in bold and italic – over-expressed, small font – suppressed.
  2. *- genes appearing in more than in one network.