Figure 2From: Modulating effect of the PI3-kinase inhibitor LY294002 on cisplatin in human pancreatic cancer cellsAkt activation caused by cisplatin stimulation. Western blotting shows the status of Akt activation using phospho-Akt antibody. Akt was phosphorylated at cisplatin concentrations over 5 μmol/L in both cell lines 6 hours after treatment. This phosphorylation was blocked by the addition of 10 μmol/L of LY294002.Back to article page