Table 2 Genotype distribution in lung cancer and Allele frequency
Allele frequency | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genotype | patients (n = 108) | controls (n = 121) | crude | adjusted | patients | controls | ||||||
n | % | n | % | OR (95%CI) | P-value | OR (95%CI)a | P-value | % | % | |||
OGG1 | ||||||||||||
Ser/Ser | 27 | 25.0 | 39 | 32.2 | 1.00 | 1.00 | Ser | 0.505 | 0.546 | |||
Ser/Cys | 55 | 50.9 | 54 | 44.6 | 1.47 (0.79–2.73) | 0.221 | 1.52 (0.80–2.91) | 0.204 | Cys | 0.495 | 0.455 | |
Cys/Cys | 26 | 24.1 | 28 | 23.1 | 1.34 (0.65–2.77) | 0.427 | 1.47 (0.69–3.12) | 0.313 | ||||
MUTYH | ||||||||||||
Gln/Gln | 22 | 20.3 | 37 | 30.6 | 1.00 | 1.00 | Gln | 0.468 | 0.591 | |||
Gln/His | 57 | 52.8 | 69 | 57.0 | 1.39 (0.74–2.62) | 0.309 | 1.35 (0.70–2.61) | 0.376 | His | 0.532 | 0.409 | |
His/His | 29 | 26.9 | 15 | 12.4 | 3.25 (1.44–7.36) | 0.005 | 3.03 (1.31–7.00) | 0.010 | ||||