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Table 1 Histological findings and Cdx2 expression in the rat model of esophageal carcinogenesis.

From: CDX2 hox gene product in a rat model of esophageal cancer

Histology

 

Cdx2 expression

Group A (<10 weeks, n = 22)

Group B (10–30 weeks, n = 22)

Group C (>30 weeks, n = 20)

   

cases (%)

cases (%)

cases (%)

Non-ulcerative esophagitis

-

22/22

(100.0%)

22/22

(100.0%)

20/20

(100.0%)

Inflammatory-ulcerative lesions

+

15/22

(68.2%)

14/22

(63.6%)

16/20

(80.0%)

Regenerative-hyperplastic lesions

+

10/22

(45.5%)

8/22

(36.4%)

10/20

(50.0%)

Metaplastic lesions

IM

+

2/22

(9.1%)

9/22

(40.9%)

12/20

(60.0%)

 

MLE

    

Carcinomas

Ac

+

0/22

(0.0%)

8/22

(36.4%)

7/20

(35.0%)

 

SCC

-

0/22

(0.0%)

2/22

(9.1%)

2/20

(10.0%)

  1. Note: n = number of cases; wks = weeks; IM = intestinal metaplasia; MLE = multilayered epithelium; Ac = adenocarcinomas; SCC = squamous cell carcinomas.