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Table 3 Major Adverse Events

From: Multicenter safety study of mFOLFOX6 for unresectable advanced/recurrent colorectal cancer in elderly patients

Grade ≥ 3

< 70 Years (n = 14)

≥ 70 Years (n = 8)

P values*

Leukocytopenia

2 [14.3%]

1 [12.5%]

0.7090

Neutropenia

4 [28.6%]

5 [62.5%]

0.1347

Anemia

0 [0.0%]

0 [0.0%]

-

Thrombocytopenia

0 [0.0%]

0 [0.0%]

-

Nausea

2 [14.3%]

0 [0.0%]

0.3939

Anorexia

1 [7.1%]

1 [12.5%]

0.6060

Fatigue

1 [7.1%]

1 [12.5%]

0.6060

Stomatitis

1 [7.1%]

0 [0.0%]

0.6363

Hand-foot syndrome

1 [7.1%]

0 [0.0%]

0.6363

Peripheral Neuropathy

   

   Grade1

12 [86.4%]

7 [87.5%]

0.7090

   Grade2

6 [45.5%]

4 [50.0%]

0.5464

   Grade3

2 [14.3%]

1 [12.5%]

0.7090

  1. Grades of adverse events were defined according to NCI-CTC v3.0
  2. *P values were calculated with the use of Fisher's exact probability test.