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Figure 2 | Journal of Experimental & Clinical Cancer Research

Figure 2

From: Methylation associated inactivation of RASSF1A and its synergistic effect with activated K-Ras in nasopharyngeal carcinoma

Figure 2

(a) Methylation-specific PCR analysis of RASSF1A promoter region in NPC primary tumors and normal nasopharyngeal tissues. Three NPCs (T12, T22, T25) and two normal nasopharyngeal (N12, N10) were showed as examples. DNA modified by methylase SssI severed as a positive methylation control and water was included as blank control. M: methylated alleles; U: unmethylated alleles. (b) Methylation status of RASSF1A in NPC cell lines CNE-1 and CNE-2, DNAs from these two cell lines could be amplified with both methylated (M) and unmethylated (U) DNA-specific primers.

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