Expression of nicotinamide N-methyltransferase in hepatocellular carcinoma is associated with poor prognosis

Table 1 Relations between NNMT mRNA levels and clinicopathologic features in HCC

	All patients (n = 120)
Clinicopathologic parameters	High NNMT (n = 48) Copy number ratio ≥ 4.40	Low NNMT (n = 72) Copy number ratio < 4.40	P value
Age			0.730
< 55 years	31	43
≥ 55 years	17	29
Gender			0.758
Male	38	54
Female	10	18
HbsAg			0.885
Absent	8	14
Present	40	58
HCV			0.823
Absent	45	67
Present	3	5
Liver cirrhosis			0.852
Absent	25	40
Present	23	32
Tumor stage			0.010
I	23	23
II	9	33
III & IV	16	16
AFP level			0.314
< 100 ng/ml	28	34
≥ 100 ng/ml	20	38
Tumor size			0.733
< 5 cm	27	44
≥ 5 cm	21	28
Edmondson grade			0.368
I	13	15
II	30	43
III & IV	5	14

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