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Table 2 Clinicopathological factors and p53AIP1 or survivin expression for overall survival in univariate and multivariate Cox regression analysis

From: Combination of p53AIP1 and survivin expression is a powerful prognostic marker in non-small cell lung cancer

Characteristics

Univariate analysis

Multivariate analysis

  

HR (95%CI)

p

HR (95%CI)

p

Age

<70

1

0.55

 

0.86

 

≥70

1.34 (0.52–3.48)

   

Tumor

T1

1

0.63

 

0.93

 

T2

1.08 (0.14–8.58)

   
 

T3

1.72 (0.21–14.0)

   

Nodal status

N0

1

0.47

 

0.89

 

N1

1.46 (0.52–4.17)

   

Histologic type

Ad

1

0.23

 

0.06

 

Sq

0.41 (0.11–1.49)

   
 

others

0.28 (0.06–1.25)

   

survivin

(+)

1

0.36

 

0.19

 

(-)

0.62 (0.22–1.75)

   

p53AIP1

(+)

1

0.04*

 

0.48

 

(-)

2.67 (0.99–7.25)

   

Combination

  

0.04*

 

0.03*

p53AIP1 (-) survivin (+)

 

1

 

1

 

p53AIP1 (+) survivin (+)

 

0.31 (0.09–1.0)

 

0.21(0.01–1.66)

 

p53AIP1 (+) survivin (-)

 

0.12 (0.02–0.97)

 

0.01 (0.002–0.28)

 

p53AIP1 (-) survivin (-)

 

0.46(0.12–1.7)

 

0.01(0.002–3.1)

 
  1. Ad, adenocarcinoma; Sq, squarmous cell carcinoma
  2. * statistically significant