Table 8 The genotype and allele frequency and odds ratios (OR) of the Arg399Gln polymorphism of XRCC1 gene in squamous cell carcinoma of the head and neck (HNSCC) patients and the controls with positive smoking status.
Genotype Allele | HNSCC patients (n = 66) Number (frequency) | Controls (n = 52) Number (frequency) | OR (95% CI) |
|---|---|---|---|
Arg/Arg | 19 (0.29) | 36 (0.69) | 0.18 (0.08 – 0.39) |
Arg/Gln | 36 (0.55) | 16 (0.31) | 2.70 (1.26 – 5.78) |
Gln/Gln | 11 (0.16) | 0 (0.00) | --------- |
Arg | 74 (0.56) | 88 (0.85) | 0.22 (0.12 – 0.41) |
Gln | 58 (0.44) | 16 (0.15) | 4.31 (2.29 – 8.13) |