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Figure 4 | Journal of Experimental & Clinical Cancer Research

Figure 4

From: The effect of high frequency steep pulsed electric fields on in vitro and in vivo antitumor efficiency of ovarian cancer cell line skov3 and potential use in electrochemotherapy

Figure 4

Routine pathologic observation of SKOV3 subcutaneous implanted tumor in BALB/c nude mice. 4A. Cancer tissue in the control group grew actively and presented with sheet distribution, high cellularity of cancer cells, multinucleate cancer cells and increased signs of pathologic mitosis. (HE × 400). 4B. Three days after exposure to SPEF (5 kHz), extensive necrosis could be seen in cancer tissue. (HE × 200).

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