Figure 6From: The effect of high frequency steep pulsed electric fields on in vitro and in vivo antitumor efficiency of ovarian cancer cell line skov3 and potential use in electrochemotherapyMicrophotos of SKOV3 subcutaneous implanted tumor under TEM observation. (TEM × 10000). 6A: In response to SPEF exposure (1 kHz), the integrality of cell membrane was destroyed along with pyknosis, karyorrhexis and karyolysis. 6B: Typical characteristic of apoptosis was further induced by SPEF exposure (5 kHz).Back to article page