Figure 2

Chromosomal Structural Mutations in Biliary Tract Cancers. (a) A cumulative depiction of the copy number changes across the genome for all biliary cancer specimens is shown. Chromosomal number is listed on the left. Amplification is depicted in red and deletion in blue. White is unchanged from genomic DNA controls. Increased amplification or deletion within a cancer specimen is reflected in increased color intensity. The percentage of patient specimens that have either amplifications or deletions at each chromosomal loci is shown for (b) EHC, (c) IHC, (d) GBC, and (e) all biliary tract cancers combined.