Skip to main content

Table 2 The drug senstivity experimental results of K562 cells

From: HA117 gene increased the multidrug resistance of K562 cells in vitro: an investigation to the function of a novel gene related to drug resistance

Drugs inhibitory concentration(IC50)
  K562 *K562/Ad-HA117 *K562/Ad-null
VCR 0.052 ± 0.009 0.810 ± 0.060 0.031 ± 0.010
ADM 0.203 ± 0.018 0.985 ± 0.12 0.210 ± 0.014
VP-16 3.221 ± 0.021 7.834 ± 0.002 3.132 ± 0.031
DNR 0.089 ± 0.025 0.654 ± 0.203 0.091 ± 0.013
MMC 3.421 ± 0.215 11.023 ± 0.542 3.203 ± 0.189
CTX 1.654 ± 0.104 5.003 ± 0.006 1.721 ± 0.056
  1. notice: *P < 0.05, compared with K562 and K562/Ad-null.