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Table 2 The drug senstivity experimental results of K562 cells

From: HA117 gene increased the multidrug resistance of K562 cells in vitro: an investigation to the function of a novel gene related to drug resistance

Drugs

inhibitory concentration(IC50)

 

K562

*K562/Ad-HA117

*K562/Ad-null

VCR

0.052 ± 0.009

0.810 ± 0.060

0.031 ± 0.010

ADM

0.203 ± 0.018

0.985 ± 0.12

0.210 ± 0.014

VP-16

3.221 ± 0.021

7.834 ± 0.002

3.132 ± 0.031

DNR

0.089 ± 0.025

0.654 ± 0.203

0.091 ± 0.013

MMC

3.421 ± 0.215

11.023 ± 0.542

3.203 ± 0.189

CTX

1.654 ± 0.104

5.003 ± 0.006

1.721 ± 0.056

  1. notice: *P < 0.05, compared with K562 and K562/Ad-null.