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Table 1 Protocol and effect of DMBA-induced oral carcinogenesis on cheek pouch of syrian hamster

From: The expression profile of microRNAs in a model of 7,12-dimethyl-benz[a]anthrance-induced oral carcinogenesis in Syrian hamster

Group

Animals

Treatment protocol

Histological type

Mean diameter of tumors

   

NM

PP

CIS

SCC

(mm)

Experiment Group

       

A

7

5%DMBA-12 week-killed

0

1

1

5

5 ± 1.69

B

7

5%DMBA-18 week-killed

0

0

0

7

8.7 ± 2.55

Control Group

       

C

8

No treatment-18 week-killed

8

0

0

0

-

  1. 5%DMBA:7,12-dimethyl benz [a]anthrance in acetone;
  2. NM:normal;PP:papilloma;CIS:carcinoma in situ;SCC:squamous cell carcinoma