Table 2 Expression of p-ERK1/2 and PI3-K as determined by immunohistochemistry, and clinicopathological variables in 108 patients with gallbladder adenocarcinoma.
Group | Total | pERK1/2 + (%) | P value | PI3-K + (%) | P value |
|---|---|---|---|---|---|
Sex | |||||
Female | 77 | 47 (61.0) | >0.05 | 41(53.2) | >0.05 |
Male | 31 | 16(51.6) | 14(45.2) | ||
Age | |||||
≤45 | 24 | 12(50) | >0.05 | 12(50) | >0.05 |
>45 | 84 | 51(60.7) | 43(51.2) | ||
Tumor diameter | |||||
<2.0 cm | 31 | 13(41.9) | <0.05 | 11(35.5) | <0.05 |
≥2.0 cm | 77 | 50(64.9) | 44(57.1) | ||
Lympho node metastasis | |||||
No | 49 | 20(40.8) | <0.01 | 16(32.7) | <0.01 |
Yes | 59 | 43(72.9) | 39(66.1) | ||
Surrounding tissue invasion | |||||
No | 49 | 21(42.9) | <0.01 | 17(34.7) | <0.01 |
Yes | 59 | 42(71.2) | 38(64.4) | ||
Gallstones | |||||
No | 50 | 24(48.0) | <0.05 | 22(44) | >0.05 |
Yes | 58 | 36(67.2) | 33(56.9) |