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Table 2 Comparison of the cytotoxic effects of cisplatin, 5-fluorouracil, doxorubicin, paclitaxel or etoposideon on parental EC109 and EC109/R subline.

From: Fractionated irradiation induced radio-resistant esophageal cancer EC109 cells seem to be more sensitive to chemotherapeutic drugs

 

IC50(uM)

Cells

Cisplatin

5-Fluorouracil

Doxorubicin

Paclitaxel

Etoposide

EC109

10.99

923.8

0.67

0.0263

9.46

EC109/R

19.24

299

0.294

0.0169

7.69

Resistance index*

1.75

0.324

0.44

0.64

0.81

  1. *Resistance index = (IC50 on EC109/R)/(IC50 on EC109)
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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