Table 1 Characteristics of case-control studies for lung cancer and IGF-I and IGFBP-3
From: IGF-I and IGFBP-3 and the risk of lung cancer: A meta-analysis based on nested case-control studies
Study | Year, location | Sample size (case/control) | Measurement | OR(95%CI) for IGF-I | OR(95%CI) for IGFBP-3 | Adjusted factors in the model in original report | |
|---|---|---|---|---|---|---|---|
| Â | Â | Â | IGF-1 | IGFBP3 | Â | Â | Â |
Lukanova et al.[14] | 2001, USA | 93/186 | RIA | RIA | 0.54(0.14–2.07) | 0.90(0.28–2.85) | Age, date of recruitment in the study, menopausal status, current smoking, time since last meal, cotinine and BMI |
London et al.[15] | 2002, China | 230/740 | RIA | IRMA | 0.86(0.47–1.57) | 0.50(0.25–1.02) | Smoking |
Spitz et al.[16] | 2002, USA | 159/297 | ELISA | ELISA | 0.64(0.31–1.33) | 2.35(1.13–4.92) | Age, sex, race, year of enrollment, and year of blood draw, BMI, smoking status, pack-years of smoking, exposure population |
Waikai et al.[17] | 2002, Japan | 194/9351 | IRMA | IRMA | 1.74(1.08–2.81) | 0.67(0.45–1.01) | Age, area, gender, smoking habits, and BMI |
Ahn et al.[18] | 2006, Finland | 200/400 | ELISA | ELISA | 0.76(0.39–1.49) | 0.71(0.35–1.47) | Age, intervention arm, BMI, and years of smoking |
Morris et al. [19] | 2006, British | 167/498 | ELISA | ELISA | 1.21(0.62–2.35) | 1.70(0.87–3.30) | Age, smoking |