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Table 2 Association of LVD and FVD with clinical and pathological parameters

From: The role of VEGF-C/D and Flt-4 in the lymphatic metastasis of early-stage invasive cervical carcinoma

Variables n LVD FVD
   mean ± SD P mean ± SD P
Catamenia      
   Premenopause 68 17.00 ± 1.63 NS 25.97 ± 1.48 NS
   Postmenopause 29 16.33 ± 1.44   25.41 ± 1.83  
Tumor size (cm)      
   ≤4 61 16.66 ± 1.26 NS 26.32 ± 1.92 NS
   >4 36 17.06 ± 1.22   26.97 ± 1.84  
Stromal invasion      
   ≤2/3 40 16.29 ± 0.86 NS 25.82 ± 1.66 NS
   >2/3 57 16.69 ± 1.23   26.02 ± 1.70  
FIGO stage      
   a 16 16.43 ± 1.40 NS* 25.09 ± 1.49 0.032*
   b 33 17.07 ± 1.49   25.21 ± 1.62  
   a 48 17.10 ± 1.52   26.10 ± 1.85  
Histological grade      
   HG1 21 16.86 ± 1.57 NS* 25.43 ± 1.98 NS*
   HG2 31 17.15 ± 1.14   26.08 ± 1.75  
   HG3 45 17.24 ± 1.37   25.76 ± 1.37  
Lymph node metastasis      
   Negative 67 17.15 ± 1.49 0.025 25.70 ± 1.84 NS
   Positive 30 17.93 ± 1.70   26.33 ± 1.82  
LVI      
   Negative 39 16.49 ± 1.46 0.001 25.97 ± 1.66 NS
   Positive 58 17.66 ± 1.82   26.50 ± 1.74  
Histological cell type      
   SCC 81 16.76 ± 1.62 NS 25.78 ± 1.64 NS
   ADE 16 17.25 ± 1.26   26.00 ± 1.15  
  1. Abbreviations: HG, histological grade; LVI, lymphatic vessel invasion; SCC, squamous cell carcinoma; ADE, adenocarcinoma, LVD, lymphatic vessels density; and FVD, Flt-4-positive vessel density. P, t-test; P*, one-way ANOVA test.