GTPase regulator associated with the focal adhesion kinase (GRAF) transcript was down-regulated in patients with myeloid malignancies

Table 1 clinical and laboratory features of patients with myeloid malignancies

Parameter	AML	CML	MDS
Age, median (range) (years)^a	54(2-86)	52(11-75)	63(39-85)
Sex (male/female)	44/28	8/7	5/2
WBC (×10⁹/l)^a	7.5(0.3-203.6)	83.4(2.8-168.7)	3.6(1.6-12.2)
Haemoglobin (g/dl)^a	71(24-123)	91(50-134)	64(46-91)
Platelet count (×10⁹/l)^a	40(3-447)	200(20-850)	50(10-926)
Cytogenetics
Good	22		3
Intermediate	35		3
Poor	8		1
CD34(+/-)	35/26
GRAF level^a	3.88(0.01-169.75)^b	23.51(0.01-157.42)^c	10.20(0.25-45.90)^b

WBC, white blood cells; ^aMedian (range); ^bP < 0.001, compared with control; ^cP = 0.030, compared with control;

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