Figure 2

ERα expression in noninvasive breast lesions. a: ERα staining in epithelial cells of normal ducts (smaller arrow) and usual ductal hyperplasia (bigger arrow) of breast was located in nuclear. b: ERα staining was seen in all epithelial cells of a normal duct (smaller arrow) but was reduced in cells in a co-existing duct with atypical ductal hyperplasia (bigger arrow). c: The arrow shows a breast duct with atypical ductal hyperplasia with positive staining of ERα (> 10%) which was absent in some cells. d: ERα staining in a ductal carcinoma in situ was negative (< 10%). The arrow shows the necrosis. (× 40)