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Table 3 Staining rate of P-gp, MRP and GSH/GST fluorescent cells analyzed by flow cytometry.

From: Comparison of the multi-drug resistant human hepatocellular carcinoma cell line Bel-7402/ADM model established by three methods

Cell

Expression rate (%, x ¯ ± s)

 

P-gp

MRP

GSH/GST

Bel-7402 (Parent)

19.59 ± 0.62

21.29 ± 1.14

26.92 ± 1.79

Bel-7402/ADMS

65.92 ± 1.41

56.88 ± 1.49

27.76 ± 1.00

Bel-7402/ADML

68.10 ± 1.88

58.84 ± 2.35

28.97 ± 1.42

Bel-7402/ADMV

91.93 ± 2.49

78.28 ± 1.23

27.57 ± 1.24

F

1512.300

1064.757

1.890

P

0.000

0.000

0.172

  1. Notes: By LSD paired-comparison in both P-gp and MRP groups, except for Bel-7402/ADML vs. Bel-7402/ADMS (P > 0.05), there was no statistical significance. In other groups of resistant cells, there was a significant difference by paired-comparison (P < 0.01). In addition, for GSH/GST, there was no statistical significance by paired-comparison (P > 0.05).
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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