Inhibitory effect of oral administration of statins on lung metastasis. B16BL6 cells were injected into the tail veins of syngeneic C57BL/6J mice. Mice were treated daily from days 1 to 14 with 10 mg/kg fluvastatin or simvastatin. After 14 d, visible nodules that had metastasized to the lungs were counted. The results are expressed as the mean ± SD for 9 mice.