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Table 5 Comparison on Logistic Regression Analyses between North American and Malaysian Samples.

From: A case-controlled validation study of a blood-based seven-gene biomarker panel for colorectal cancer in Malaysia

Study Location

North American

Malaysian

 

Training Set

Test Set

 

Sample Size

232

410

210

CRC

112

202

99

Control

120

208

111

Cut-off Value

P = 0.5

P = 0.5

P = 0.5

Area under ROC Curve

(95% CI)

0.80

(0.74 - 0.85)

0.80

(0.76 - 0.84)

0.76

(0.70 - 0.82)

Significant Level

P < 0.0001

P < 0.0001

P < 0.0001

Sensitivity

82%

72%

61%

Specificity

64%

70%

77%

Accuracy

73%

71%

70%

  1. Note: The MedCalc software, version 11.3 (Broekstraat 52, Mariakerke, Belgium) was used for the statistical analysis. CI denotes confidence interval.