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Table 5 Comparison on Logistic Regression Analyses between North American and Malaysian Samples.

From: A case-controlled validation study of a blood-based seven-gene biomarker panel for colorectal cancer in Malaysia

Study Location North American Malaysian
  Training Set Test Set  
Sample Size 232 410 210
CRC 112 202 99
Control 120 208 111
Cut-off Value P = 0.5 P = 0.5 P = 0.5
Area under ROC Curve
(95% CI)
0.80
(0.74 - 0.85)
0.80
(0.76 - 0.84)
0.76
(0.70 - 0.82)
Significant Level P < 0.0001 P < 0.0001 P < 0.0001
Sensitivity 82% 72% 61%
Specificity 64% 70% 77%
Accuracy 73% 71% 70%
  1. Note: The MedCalc software, version 11.3 (Broekstraat 52, Mariakerke, Belgium) was used for the statistical analysis. CI denotes confidence interval.