Figure 4
DKK-1 concentration in sera (A) and cerebral fluid (B) samples determined by ELISA in patients with tumors and in healthy controls. *, difference between the glioma group and neuronal benign tumor group. **, difference between the glioma group and normal control group. ***, difference between the neuronal benign tumor group and healthy control group. The DKK-1 concentration in cerebral fluid is increased in glioma, and differences may exist among different glioma grades, suggesting the role of DKK-1 in glioma pathogenesis.