8-oxo-7,8-dihydro-2'-deoxyguanosine as a biomarker of oxidative damage in oesophageal cancer patients: lack of association with antioxidant vitamins and polymorphism of hOGG1 and GST

Table 2 Biochemical parameters of the study group

*Parameter*	*Patients (mean ± s.d.)*	*Controls (mean ± s.d.)*	*P-value* ^b *patient vs. control*
8-oxodG/10 ⁶ 2'dG ^c	7.2 ± 2.6 (n = 17)	4.9 ± 1.9 (n = 43)	P < 0.001
Vitamin A (μM)	2.77 ± 0.94 (n = 15)^a	2.74 ± 0.61 (n = 42)^a	P = 0.895
Vitamin E (μM)	34.77 ± 12.27 (n = 15)^a	38.73 ± 9.47 (n = 42)^a	P = 0.204

PBMCs were collected and processed for measuring 8-oxodG. Vitamins were extracted from the serum samples for estimation. ^a Numbers in parentheses indicate the number of samples analysed as some samples had to be omitted due to insufficient volume of serum collected. A total of 57 out of the 60 samples were analysed for vitamins. ^b Student's t-test was applied. ^c Values taken from our data published earlier [10].

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