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Figure 2 | Journal of Experimental & Clinical Cancer Research

Figure 2

From: All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax protein

Figure 2

ATRA induces apoptotic cell death in GIST-T1 cells. Panel A shows the shrinkage and fragmentation of nuclei in GIST-T1 cells after 6-day treatment with 180 μM ATRA compared with the control cells. Panel B shows the result of DNA fragmentation after 2-, 4- or 6-day treatment with 180 μM ATRA. Panel C shows the presence of cleaved caspase-3 and cleaved PARP after 2-, 4- or 6-day treatment with 180 μM ATRA.

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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