Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Figure 2 | Journal of Experimental & Clinical Cancer Research

Figure 2

From: All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax protein

Figure 2

ATRA induces apoptotic cell death in GIST-T1 cells. Panel A shows the shrinkage and fragmentation of nuclei in GIST-T1 cells after 6-day treatment with 180 μM ATRA compared with the control cells. Panel B shows the result of DNA fragmentation after 2-, 4- or 6-day treatment with 180 μM ATRA. Panel C shows the presence of cleaved caspase-3 and cleaved PARP after 2-, 4- or 6-day treatment with 180 μM ATRA.

Back to article page