Table 3 Allele frequencies of SLC2A1, VEGFA, APEX1, and HIF1A polymorphisms
Target gene polymorphism (rs number) | Genotype | No. patients | (%) | Allele frequencies | Â | Hardy-Weinberg equilibrium |
|---|---|---|---|---|---|---|
SLC2A1 -2841A>T | AA | 78 | (51.7%) | A:T | 0.705:0.295 | 0.2579 |
(rs710218) | AT | 57 | (37.7%) | Â | Â | Â |
| Â | TT | 16 | (10.6%) | Â | Â | Â |
VEGFA +936C>T | CC | 102 | (67.1%) | C:T | 0.819:0.181 | 0.2579 |
(rs3025039) | CT | 45 | (29.6%) | Â | Â | Â |
| Â | TT | 5 | (3.3%) | Â | Â | Â |
APEX1 Asp148Glu | TT | 55 | (36.4%) | T:G | 0.589:0.411 | 0.3929 |
(rs1130409) | TG | 68 | (45.0%) | Â | Â | Â |
| Â | GG | 28 | (18.5%) | Â | Â | Â |
HIF1A Pro582Ser | CC | 139 | (90.8%) | C:T | 0.954:0.046 | 0.5541 |
(rs11549465) | CT | 14 | (9.2%) | Â | Â | Â |
| Â | TT | 0 | (0.0%) | Â | Â | Â |
HIF1A Ala588Thr | GG | 137 | (90.1%) | G:A | 0.951:0.049 | 0.5219 |
(rs11549467) | GA | 15 | (9.9%) | Â | Â | Â |
| Â | AA | 0 | (0.0%) | Â | Â | Â |