Figure 5From: Breast cancer stromal fibroblasts promote the generation of CD44+CD24- cells through SDF-1/CXCR4 interactionMammosphere cells and monolayer cells were cultured in the presence of 1 μg/ml AMD3100 for 48 h. qRT-PCR showed that CXCR4 mRNA expression in mammosphere cells was 3.9 fold higher than that in monolayer cells, (P < 0.01), and AMD3100 could significantly down-regulate it in both when treated for 48 h.Back to article page