Table 2 Other cyclophilins in human cancers
Cancer type | Isoforms | Implications in cancers | Contributers |
|---|---|---|---|
Breast cancer | CypB | A transcription inducer | Fang et al., Am J Pathol. (2009). |
Breast cancer | Cyp40 | Having important functional implications for ER alpha and other steroid receptors in breast cancer | Eliseev etal., J Biol Chem. (2009) |
| Â | Â | Increasing in response to high temperature stress | Machida etal., J Biol Chem. (2006) |
Breast cancer | CypC | Binding to osteopontin via CD147 and increase in migration and invasion | Mi Z et al., Cancer Res. (2007) |
Tumors of the breast, ovary, and uterus | CypD | Inhibition of PT-pore | Marzo et al., Cancer Res. (2007) |
| Â | Â | Interacton with Bcl2 | Eliseev etal., J Biol Chem. (2009) |