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Table 3 HER2 expression in relation to main tumor cheracteristics and treatment response

From: Evaluation of HER2 and p53 expression in predicting response to docetaxel-based first-line chemotherapy in advanced breast cancer

  HER2 expression"
  Total Low High p value
Age     
   < 55 yrs 18 13 5 n.s.
   ≥55 yrs 18 14 4  
ER expression     
   Negative 14 10 4 n.s.
   Positive 22 17 5  
PgR expression     
   Negative 13 9 4 n.s.
   Positive 23 18 5  
Grading #     
   G2 21 18 3 0.05
   G3 15 8 7  
Stage    
   I-IIA 17 16 1 0.003
   IIB-III 16 8 8  
Ki67     
   Negative 22 18 4 n.s.
   Positive 14 9 5  
Treatment response     
   CR+PR 15 9 6 0.046
   SD+PD 21 18 3  
  1. "IHC 0, 1+ and 2+ FISH negative were regarded as negative while IHC 3+ or 2+ FISH positive were regarded as positive. #According to Elston and Ellis classification (see text for complete reference). *According to UICC-TNM classification of malignant tumours, sixth edition 2002. °At initial diagnosis time. n.s. = not significant; CR = complete response; PR = partial response; SD = stable disease; PD = disease progression.