Figure 2
Determination of the effective concentration for COX-2 mediated VEGF up-regulation in NSCLC cells. (A) In A549 cells, red, purple, green and blue curves represented COX-2 concentrations of 0, 9.17 × 10-12mol/ml, 1.83 × 10-11mol/ml, and 7.34 × 10-11mol/ml, with G-mean fluorescence intensity of 26.32, 32.93, 35.45, and 39.98, respectively. (B) In H460 cells, red, purple and green curves represented COX-2 concentrations of 0, 9.17 × 10-12mol/ml, 3.67 × 10-11mol/ml, with G-mean fluorescence intensity of 25.33, 29.56, and 34.99, respectively. (C) I n A431 cells, red, purple, green and blue curves represented COX-2 concentrations of 0, 9.17 × 10-12mol/ml, 1.83 × 10-11mol/ml, and 7.34 × 10-11mol/ml, with G-mean fluorescence intensity of 25.98, 33.23, 36.09, and 38.89, respectively. (D) COX-2 mediated VEGF up-regulation was shown. G-mean, geometric mean.