Table 2 Multivariate analysis of VEGF and MVD expression in NSCLC specimens
VEGF expression | MVD expression | |||||
|---|---|---|---|---|---|---|
β | HR (95% CI) | P | β | HR (95% CI) | P | |
COX-2 expression | ||||||
High | 2.286 | 9.836 (3.387 - 28.564) | 0.000 | 1.146 | 3.147 (1.152 - 8.598) | 0.025 |
Low | 1.000 | 1.000 | ||||
TNM stage | ||||||
III + IV | 0.061 | 1.063 (0.493 - 2.289) | 0.877 | 0.025 | 1.025 (0.493 - 2.132) | 0.947 |
I + II | 1.000 | 1.000 | ||||
Histology | ||||||
Adeno | -0.300 | 0.741 (0.303 - 1.810) | 0.510 | 0.400 | 1.491 (0.649 - 3.425) | 0.346 |
SCC | 1.000 | 1.000 | ||||
Differentiation | ||||||
Poor | -0.292 | 0.746 (0.198 - 2.809) | 0.665 | -0.969 | 0.379 (0.106 - 1.359) | 0.137 |
Well and moderate | 1.000 | 1.000 | ||||
Smoking | ||||||
Yes | -0.775 | 0.461 (0.145 - 1.461) | 0.188 | -0.481 | 0.618 (0.214 - 1.785) | 0.374 |
No | 1.000 | 1.000 | ||||
Sex | ||||||
Male | -1.005 | 0.366 (0.101 - 1.330) | 0.127 | -0.511 | 0.600 (0.170 - 2.110) | 0.426 |
Female | 1.000 | 1.000 | ||||
Age | ||||||
≥ 60 yrs | 0.316 | 1.371 (0.413 - 4.551) | 0.606 | -0.223 | 0.800 (0.251 - 2.551) | 0.706 |
< 60 yrs | 1.000 | 1.000 |