Table 1 Primer sequences used for qRT-PCR

Nm23

F: 5'-ACC TGA AGG ACC GTC CAT TCT TTG C-3'

R: 5'-GGG TGA AAC CAC AAG CCG ATC TCC T-3'

KISS1

F: 5'-ACC TGC CTC TTC TCA CCA AG-3'

R: 5'-TAG CAG CTG GCT TCC TCT C-3'

Mkk4

F: 5'-GCA ACT TGA AAG CAC TAA ACC-3'

R: 5'-CAT GTA TGG CCT ACA GCC AG-3'

RRM1

F: 5'-ACT AAG CAC CCT GAC TAT GCT ATC C-3'

R: 5'-CTT CCA TCA CAT CAC TGA ACA CTT T-3'

KAI1

F: 5'-CAT GAA TCG CCC TGA GGT CAC CTA-3'

R: 5'-GCC TGC ACC TTC TCC ATG CAG CCC-3'

BRMS1

F: 5'-ACT GAG TCA GCT GCG GTT GCG G-3'

R: 5'-AAG ACC TGG AGC TGC CTC TGG CGT GC-3'

MMP1

F: 5'-CTG TTC AGG GAC AGA ATG TGC T-3'

R: 5'-TCG ATA TGC TTC ACA GTT CTA GGG-3'

MMP2

F: 5'-TCA CTC CTG AGA TCT GCA AAC AG-3'

R: 5'-TCA CAG TCC GCC AAA TGA AC-3'

MMP9

F: 5'-CCC TGG AGA CCT GAG AAC CA-3'

R: 5'-CCA CCC GAG TGT AAC CAT AGC-3'

MMP13

F: 5'-TCC TCT TCT TGA GCT GGA CTC ATT-3'

R: 5'-CGC TCT GCA AAC TGG AGG TC-3'

MMP14

F: 5'-TGC CTG CGT CCA TCA ACA CT-3'

R: 5'-CAT CAA ACA CCC AAT GCT TGT C-3'

ITGA5

F: 5'-GTC GGG GGC TTC AAC TTA GAC-3'

R: 5'-CCT GGC TGG CTG GTA TTA GC-3'

18S rRNA

F: 5'-TAC CTG GTT GAT CCT GCC AG-3'

R: 5'-GAG CTC ACC GGG TTG GTT TTG-3'