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Figure 1 | Journal of Experimental & Clinical Cancer Research

Figure 1

From: Adenovirus-mediated delivery of bFGF small interfering RNA reduces STAT3 phosphorylation and induces the depolarization of mitochondria and apoptosis in glioma cells U251

Figure 1

Ad-bFGF-siRNA reduces STAT3 phosphorylation in U251 cells. (A) Western blot analysis revealed that the levels of pSTAT3 (Tyr705) and pJAK2 are higher in U251 cells than in normal human astrocytes (NHA). (B) Ad-bFGF-siRNA (MOI = 100) reduces STAT3 phosphorylation (both Tyr705 and Ser727) in a time-dependent manner in U251 cells. Total STAT3 expression remains stable.

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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