Figure 1

Association of NF-κB and Notch1 expression with lymph node metastasis in ESCC. (A) Compared with samples of ESCC without lymph node involvement, the samples of ESCC with lymph node involvement showed high levels of NF-κB expression and low levels of Notch1 expression (magnification, ×200). (B) In ESCC tissue with lymph node involvement, NF-κB staining was strong (mean histoscore, 5.55 ± 0.41) and Notch1 staining was weak (mean histoscore, 3.41 ± 0.36) compared with tissues without lymph node involvement (mean histoscores, 4.90 ± 0.43 and 4.27 ± 0.27 for NF-κB and Notch1, respectively; P < 0.05 for both).